Solid-Phase Synthesis of Chiral N-Acylethylenediamines and Their Use as Ligands for the Asymmetric Addition of Alkylzinc and Alkenylzinc Reagents to Aldehydes

A solid-phase procedure has been developed for the synthesis of chiral N-acylethylenediamine ligands. The ligands are obtained in good yield and purity, without the need for chromatography or other purification methods. Several new and previously reported ligands were prepared using this procedure....

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Veröffentlicht in:Journal of organic chemistry 2004-10, Vol.69 (20), p.6666-6673
Hauptverfasser: Sprout, Christopher M, Richmond, Meaghan L, Seto, Christopher T
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Sprache:eng
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