Immunoglobulins and complement in postmortem multiple sclerosis tissue

Objective To identify evidence of a discrete, specific immune response in multiple sclerosis (MS) by analyzing the distribution of immunoglobulins and complement in tissue derived from cases of MS, and from control inflammatory white matter diseases known to express viral and autoantigens in the bra...

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Veröffentlicht in:	Annals of neurology 2009-01, Vol.65 (1), p.32-46
Hauptverfasser:	Barnett, Michael H., Parratt, John D. E., Cho, Eun-Sook, Prineas, John W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Biological and medical sciences Brain - metabolism Brain - pathology Complement C3d - immunology Complement C3d - metabolism Complement C9 - immunology Complement C9 - metabolism Cytomegalovirus Female Humans Immunoglobulins - immunology Immunoglobulins - metabolism Male Medical sciences Middle Aged Multiple Sclerosis - immunology Multiple Sclerosis - pathology Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis Nervous System Diseases - classification Nervous System Diseases - metabolism Nervous System Diseases - pathology Neurology Postmortem Changes Spinal Cord - metabolism Spinal Cord - pathology Young Adult
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