Preparation and radiolabeling of human serum albumin (HSA)-coated magnetite nanoparticles for magnetically targeted therapy
In this paper, we describe the preparation of human serum albumin-coated magnetic particles of about 200 nm in diameter with narrow size distribution radiolabeled with 188Re for the purpose of magnetically targeted therapy. The optimum radiolabeling conditions are: SnCl 2·2H 2O 8 mg/ml, citric acid...
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| Veröffentlicht in: | Applied radiation and isotopes 2004-12, Vol.61 (6), p.1255-1259 |
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| container_title | Applied radiation and isotopes |
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| creator | Chunfu, Zhang Jinquan, Cao Duanzhi, Yin Yongxian, Wang Yanlin, Feng Jiajü, Tan |
| description | In this paper, we describe the preparation of human serum albumin-coated magnetic particles of about 200
nm in diameter with narrow size distribution radiolabeled with
188Re for the purpose of magnetically targeted therapy. The optimum radiolabeling conditions are: SnCl
2·2H
2O 8
mg/ml, citric acid 20
mg/ml, vitamin C 8
mg/ml, labeling volume 500
μl and a reaction time of 3
h. The stability of the radiolabeled particles is suitable for in vivo study. |
| doi_str_mv | 10.1016/j.apradiso.2004.03.114 |
| format | Article |
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nm in diameter with narrow size distribution radiolabeled with
188Re for the purpose of magnetically targeted therapy. The optimum radiolabeling conditions are: SnCl
2·2H
2O 8
mg/ml, citric acid 20
mg/ml, vitamin C 8
mg/ml, labeling volume 500
μl and a reaction time of 3
h. The stability of the radiolabeled particles is suitable for in vivo study.</description><identifier>ISSN: 0969-8043</identifier><identifier>EISSN: 1872-9800</identifier><identifier>DOI: 10.1016/j.apradiso.2004.03.114</identifier><identifier>PMID: 15388118</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>188Re ; Adsorption ; Coated Materials, Biocompatible - chemical synthesis ; Coated Materials, Biocompatible - chemistry ; Drug Carriers - chemical synthesis ; Drug Carriers - chemistry ; Drug Stability ; Ferrosoferric Oxide ; HSA ; Iron - chemistry ; Isotope Labeling - methods ; Labeling ; Magnetic particle ; Magnetically targeted therapy ; Nanotubes - chemistry ; Nanotubes - ultrastructure ; Oxides - chemistry ; Particle Size ; Pest Control, Biological ; Radioisotopes - administration & dosage ; Radioisotopes - chemistry ; Radiotherapy - methods ; Rhenium ; Serum Albumin - chemistry</subject><ispartof>Applied radiation and isotopes, 2004-12, Vol.61 (6), p.1255-1259</ispartof><rights>2004 Elsevier Ltd</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c364t-1b541d1555f863efd8949910bc2740c7f8ac6b99be5aa8e8f245a6daeedc87d43</citedby><cites>FETCH-LOGICAL-c364t-1b541d1555f863efd8949910bc2740c7f8ac6b99be5aa8e8f245a6daeedc87d43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.apradiso.2004.03.114$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15388118$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chunfu, Zhang</creatorcontrib><creatorcontrib>Jinquan, Cao</creatorcontrib><creatorcontrib>Duanzhi, Yin</creatorcontrib><creatorcontrib>Yongxian, Wang</creatorcontrib><creatorcontrib>Yanlin, Feng</creatorcontrib><creatorcontrib>Jiajü, Tan</creatorcontrib><title>Preparation and radiolabeling of human serum albumin (HSA)-coated magnetite nanoparticles for magnetically targeted therapy</title><title>Applied radiation and isotopes</title><addtitle>Appl Radiat Isot</addtitle><description>In this paper, we describe the preparation of human serum albumin-coated magnetic particles of about 200
nm in diameter with narrow size distribution radiolabeled with
188Re for the purpose of magnetically targeted therapy. The optimum radiolabeling conditions are: SnCl
2·2H
2O 8
mg/ml, citric acid 20
mg/ml, vitamin C 8
mg/ml, labeling volume 500
μl and a reaction time of 3
h. The stability of the radiolabeled particles is suitable for in vivo study.</description><subject>188Re</subject><subject>Adsorption</subject><subject>Coated Materials, Biocompatible - chemical synthesis</subject><subject>Coated Materials, Biocompatible - chemistry</subject><subject>Drug Carriers - chemical synthesis</subject><subject>Drug Carriers - chemistry</subject><subject>Drug Stability</subject><subject>Ferrosoferric Oxide</subject><subject>HSA</subject><subject>Iron - chemistry</subject><subject>Isotope Labeling - methods</subject><subject>Labeling</subject><subject>Magnetic particle</subject><subject>Magnetically targeted therapy</subject><subject>Nanotubes - chemistry</subject><subject>Nanotubes - ultrastructure</subject><subject>Oxides - chemistry</subject><subject>Particle Size</subject><subject>Pest Control, Biological</subject><subject>Radioisotopes - administration & dosage</subject><subject>Radioisotopes - chemistry</subject><subject>Radiotherapy - methods</subject><subject>Rhenium</subject><subject>Serum Albumin - chemistry</subject><issn>0969-8043</issn><issn>1872-9800</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkMFu1DAQhi0EotvCK1Q-ITgk2LGTtW9UFVCkSiABZ2tiT7ZeJXawnUorXp6sdiuOPc1hvv8fzUfINWc1Z7z7uK9hTuB8jnXDmKyZqDmXL8iGq21TacXYS7JhutOVYlJckMuc92wFlW5ekwveCqU4Vxvy90fCGRIUHwOF4OixNI7Q4-jDjsaBPiwTBJoxLROFsV8mH-j7u583HyoboaCjE-wCFl-QBghxLSvejpjpENPTzsI4HmiBtMNjojxggvnwhrwaYMz49jyvyO8vn3_d3lX3379-u725r6zoZKl430rueNu2g-oEDk5pqTVnvW22ktntoMB2vdY9tgAK1dDIFjoHiM6qrZPiirw79c4p_lkwFzP5bHEcIWBcsuk6zYQUYgW7E2hTzDnhYObkJ0gHw5k5ajd786TdHLUbJsyqfQ1eny8s_YTuf-zseQU-nQBc_3z0mEy2HoNF5xPaYlz0z934BxnImlo</recordid><startdate>20041201</startdate><enddate>20041201</enddate><creator>Chunfu, Zhang</creator><creator>Jinquan, Cao</creator><creator>Duanzhi, Yin</creator><creator>Yongxian, Wang</creator><creator>Yanlin, Feng</creator><creator>Jiajü, Tan</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20041201</creationdate><title>Preparation and radiolabeling of human serum albumin (HSA)-coated magnetite nanoparticles for magnetically targeted therapy</title><author>Chunfu, Zhang ; Jinquan, Cao ; Duanzhi, Yin ; Yongxian, Wang ; Yanlin, Feng ; Jiajü, Tan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c364t-1b541d1555f863efd8949910bc2740c7f8ac6b99be5aa8e8f245a6daeedc87d43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>188Re</topic><topic>Adsorption</topic><topic>Coated Materials, Biocompatible - chemical synthesis</topic><topic>Coated Materials, Biocompatible - chemistry</topic><topic>Drug Carriers - chemical synthesis</topic><topic>Drug Carriers - chemistry</topic><topic>Drug Stability</topic><topic>Ferrosoferric Oxide</topic><topic>HSA</topic><topic>Iron - chemistry</topic><topic>Isotope Labeling - methods</topic><topic>Labeling</topic><topic>Magnetic particle</topic><topic>Magnetically targeted therapy</topic><topic>Nanotubes - chemistry</topic><topic>Nanotubes - ultrastructure</topic><topic>Oxides - chemistry</topic><topic>Particle Size</topic><topic>Pest Control, Biological</topic><topic>Radioisotopes - administration & dosage</topic><topic>Radioisotopes - chemistry</topic><topic>Radiotherapy - methods</topic><topic>Rhenium</topic><topic>Serum Albumin - chemistry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chunfu, Zhang</creatorcontrib><creatorcontrib>Jinquan, Cao</creatorcontrib><creatorcontrib>Duanzhi, Yin</creatorcontrib><creatorcontrib>Yongxian, Wang</creatorcontrib><creatorcontrib>Yanlin, Feng</creatorcontrib><creatorcontrib>Jiajü, Tan</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Applied radiation and isotopes</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chunfu, Zhang</au><au>Jinquan, Cao</au><au>Duanzhi, Yin</au><au>Yongxian, Wang</au><au>Yanlin, Feng</au><au>Jiajü, Tan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Preparation and radiolabeling of human serum albumin (HSA)-coated magnetite nanoparticles for magnetically targeted therapy</atitle><jtitle>Applied radiation and isotopes</jtitle><addtitle>Appl Radiat Isot</addtitle><date>2004-12-01</date><risdate>2004</risdate><volume>61</volume><issue>6</issue><spage>1255</spage><epage>1259</epage><pages>1255-1259</pages><issn>0969-8043</issn><eissn>1872-9800</eissn><abstract>In this paper, we describe the preparation of human serum albumin-coated magnetic particles of about 200
nm in diameter with narrow size distribution radiolabeled with
188Re for the purpose of magnetically targeted therapy. The optimum radiolabeling conditions are: SnCl
2·2H
2O 8
mg/ml, citric acid 20
mg/ml, vitamin C 8
mg/ml, labeling volume 500
μl and a reaction time of 3
h. The stability of the radiolabeled particles is suitable for in vivo study.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>15388118</pmid><doi>10.1016/j.apradiso.2004.03.114</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
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| ispartof | Applied radiation and isotopes, 2004-12, Vol.61 (6), p.1255-1259 |
| issn | 0969-8043 1872-9800 |
| language | eng |
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| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | 188Re Adsorption Coated Materials, Biocompatible - chemical synthesis Coated Materials, Biocompatible - chemistry Drug Carriers - chemical synthesis Drug Carriers - chemistry Drug Stability Ferrosoferric Oxide HSA Iron - chemistry Isotope Labeling - methods Labeling Magnetic particle Magnetically targeted therapy Nanotubes - chemistry Nanotubes - ultrastructure Oxides - chemistry Particle Size Pest Control, Biological Radioisotopes - administration & dosage Radioisotopes - chemistry Radiotherapy - methods Rhenium Serum Albumin - chemistry |
| title | Preparation and radiolabeling of human serum albumin (HSA)-coated magnetite nanoparticles for magnetically targeted therapy |
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