Setting sights on the treatment of ocular angiogenesis using antisense oligonucleotides

The application of antisense technology to study physiological and disease processes continues to mature. Antisense approaches are among the most direct means to use genomic sequence information. When developing therapeutics, applications range from early target validation in discovery to the therap...

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Veröffentlicht in:	Trends in pharmacological sciences (Regular ed.) 2004-10, Vol.25 (10), p.523-527
Hauptverfasser:	Henry, Scott P., Marcusson, Eric G., Vincent, Thomas M., Dean, Nicholas M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Inhibitors - administration & dosage Angiogenesis Inhibitors - therapeutic use Animals Disease Models, Animal Drug Delivery Systems - methods Eye Diseases - drug therapy Eye Diseases - metabolism Humans Neovascularization, Pathologic - drug therapy Neovascularization, Pathologic - metabolism Oligonucleotides, Antisense - administration & dosage Oligonucleotides, Antisense - therapeutic use
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