Compare Activities on Regulating Lipid-Metabolism and Reducing Oxidative Stress of Diabetic Rats of Tremella Aurantialba Broth's Extract (TBE) with Its Mycelia Polysaccharides (TMP)
Abnormal lipid-metabolism and elevated oxidative stress are the familiar complications of diabetic mellitus. Regulated lipid-metabolism and decreased oxidative stress have become the key indices to cure diabetic complications. The activities of broth extract (TBE) and mycelia polysaccharides (TMP) o...
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| Veröffentlicht in: | Journal of food science 2009, Vol.74 (1), p.H15-H21 |
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| creator | Zhang, Z.C Lian, B Huang, D.M Cui, F.J |
| description | Abnormal lipid-metabolism and elevated oxidative stress are the familiar complications of diabetic mellitus. Regulated lipid-metabolism and decreased oxidative stress have become the key indices to cure diabetic complications. The activities of broth extract (TBE) and mycelia polysaccharides (TMP) of Tremella aurantialba, which is one of the best-known multipurpose medicinal fungi in China, were studied using alloxan-induced diabetic rats. TBE contains saponins, while TMP contains polysaccharides. Both TBE and TMP could reduce the blood glucose levels of diabetic rats; TBE had stronger abilities to reduce the levels of total cholesterol and total triglyceride in serum, those of malondialdehyde, and enhance the activities of superoxide dismutase and glutathione reductase in different tissues of diabetic rats (P < 0.01). TBE had slightly stronger abilities to enhance the total antioxidant capability, catalase, and glutathione peroxidase in different tissues of diabetic rats, but no significant difference was found between TBE and TMP groups. All these results indicated that TBE was more capable of regulating lipid-metabolism and decreasing oxidative stress. |
| doi_str_mv | 10.1111/j.1750-3841.2008.00989.x |
| format | Article |
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Regulated lipid-metabolism and decreased oxidative stress have become the key indices to cure diabetic complications. The activities of broth extract (TBE) and mycelia polysaccharides (TMP) of Tremella aurantialba, which is one of the best-known multipurpose medicinal fungi in China, were studied using alloxan-induced diabetic rats. TBE contains saponins, while TMP contains polysaccharides. Both TBE and TMP could reduce the blood glucose levels of diabetic rats; TBE had stronger abilities to reduce the levels of total cholesterol and total triglyceride in serum, those of malondialdehyde, and enhance the activities of superoxide dismutase and glutathione reductase in different tissues of diabetic rats (P < 0.01). TBE had slightly stronger abilities to enhance the total antioxidant capability, catalase, and glutathione peroxidase in different tissues of diabetic rats, but no significant difference was found between TBE and TMP groups. All these results indicated that TBE was more capable of regulating lipid-metabolism and decreasing oxidative stress.</description><identifier>ISSN: 0022-1147</identifier><identifier>EISSN: 1750-3841</identifier><identifier>DOI: 10.1111/j.1750-3841.2008.00989.x</identifier><identifier>PMID: 19200097</identifier><identifier>CODEN: JFDSAZ</identifier><language>eng</language><publisher>Malden, USA: Blackwell Publishing Inc</publisher><subject>Agaricales - chemistry ; animal models ; Animals ; antioxidant activity ; Biological and medical sciences ; blood glucose ; Blood Glucose - drug effects ; blood lipids ; Carbohydrates ; catalase ; cholesterol ; Cholesterol - blood ; Diabetes ; diabetes mellitus ; Diabetes Mellitus, Experimental - drug therapy ; diet-related diseases ; Food industries ; Food science ; Fundamental and applied biological sciences. Psychology ; Fungi ; Glucose ; glutathione reductase (NADPH) ; Glutathione Reductase - metabolism ; human diseases ; lipid metabolism ; Lipid Metabolism - drug effects ; Lipids ; malondialdehyde ; Malondialdehyde - metabolism ; medicinal properties ; Metabolism ; mycelium ; Mycelium - chemistry ; oxidative press ; oxidative stress ; Oxidative Stress - drug effects ; plant extracts ; polysaccharides ; Polysaccharides - pharmacology ; Random Allocation ; Rats ; Rats, Wistar ; Rodents ; Saponins - pharmacology ; superoxide dismutase ; Superoxide Dismutase - metabolism ; Tremella ; Tremella aurantialba ; triacylglycerols ; Triglycerides - blood</subject><ispartof>Journal of food science, 2009, Vol.74 (1), p.H15-H21</ispartof><rights>2008 Institute of Food Technologists</rights><rights>2009 INIST-CNRS</rights><rights>Copyright Institute of Food Technologists Jan/Feb 2009</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5369-32e34cb218efc5b145efcffa94d48590a3c2feda8faf874a74f1972a78a6a4f73</citedby><cites>FETCH-LOGICAL-c5369-32e34cb218efc5b145efcffa94d48590a3c2feda8faf874a74f1972a78a6a4f73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1750-3841.2008.00989.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1750-3841.2008.00989.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>315,781,785,1418,4025,27928,27929,27930,45579,45580</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=21151824$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19200097$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zhang, Z.C</creatorcontrib><creatorcontrib>Lian, B</creatorcontrib><creatorcontrib>Huang, D.M</creatorcontrib><creatorcontrib>Cui, F.J</creatorcontrib><title>Compare Activities on Regulating Lipid-Metabolism and Reducing Oxidative Stress of Diabetic Rats of Tremella Aurantialba Broth's Extract (TBE) with Its Mycelia Polysaccharides (TMP)</title><title>Journal of food science</title><addtitle>J Food Sci</addtitle><description>Abnormal lipid-metabolism and elevated oxidative stress are the familiar complications of diabetic mellitus. Regulated lipid-metabolism and decreased oxidative stress have become the key indices to cure diabetic complications. The activities of broth extract (TBE) and mycelia polysaccharides (TMP) of Tremella aurantialba, which is one of the best-known multipurpose medicinal fungi in China, were studied using alloxan-induced diabetic rats. TBE contains saponins, while TMP contains polysaccharides. Both TBE and TMP could reduce the blood glucose levels of diabetic rats; TBE had stronger abilities to reduce the levels of total cholesterol and total triglyceride in serum, those of malondialdehyde, and enhance the activities of superoxide dismutase and glutathione reductase in different tissues of diabetic rats (P < 0.01). TBE had slightly stronger abilities to enhance the total antioxidant capability, catalase, and glutathione peroxidase in different tissues of diabetic rats, but no significant difference was found between TBE and TMP groups. All these results indicated that TBE was more capable of regulating lipid-metabolism and decreasing oxidative stress.</description><subject>Agaricales - chemistry</subject><subject>animal models</subject><subject>Animals</subject><subject>antioxidant activity</subject><subject>Biological and medical sciences</subject><subject>blood glucose</subject><subject>Blood Glucose - drug effects</subject><subject>blood lipids</subject><subject>Carbohydrates</subject><subject>catalase</subject><subject>cholesterol</subject><subject>Cholesterol - blood</subject><subject>Diabetes</subject><subject>diabetes mellitus</subject><subject>Diabetes Mellitus, Experimental - drug therapy</subject><subject>diet-related diseases</subject><subject>Food industries</subject><subject>Food science</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Fungi</subject><subject>Glucose</subject><subject>glutathione reductase (NADPH)</subject><subject>Glutathione Reductase - metabolism</subject><subject>human diseases</subject><subject>lipid metabolism</subject><subject>Lipid Metabolism - drug effects</subject><subject>Lipids</subject><subject>malondialdehyde</subject><subject>Malondialdehyde - metabolism</subject><subject>medicinal properties</subject><subject>Metabolism</subject><subject>mycelium</subject><subject>Mycelium - chemistry</subject><subject>oxidative press</subject><subject>oxidative stress</subject><subject>Oxidative Stress - drug effects</subject><subject>plant extracts</subject><subject>polysaccharides</subject><subject>Polysaccharides - pharmacology</subject><subject>Random Allocation</subject><subject>Rats</subject><subject>Rats, Wistar</subject><subject>Rodents</subject><subject>Saponins - pharmacology</subject><subject>superoxide dismutase</subject><subject>Superoxide Dismutase - metabolism</subject><subject>Tremella</subject><subject>Tremella aurantialba</subject><subject>triacylglycerols</subject><subject>Triglycerides - blood</subject><issn>0022-1147</issn><issn>1750-3841</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkctuEzEUhkcIREvhFcBCAtrFBF_m4lmw6CW9qaVVmwrExjrjsVOHuQTb0yYPxvvhaaIgscKbY_t8_9Fv_1GECB6RsD7PRiRPccx4QkYUYz7CuODFaPEs2t40nkfbGFMaE5LkW9Er52Z4OLPsZbRFiqDCRb4d_T7smjlYhfalNw_GG-VQ16IbNe1r8KadogszN1V8qTyUXW1cg6CtQr_q5dC9WpgqcA8K3XqrXBBrdGSgVN5IdAP-6WJiVaPqGtB-b6H1BuoS0IHt_P0nh8YLb0F6tDs5GO-hR-Pv0VmQXS6lqg2g665eOpDyHqypgrndyeX13uvohYbaqTfruhPdHY8nh6fxxdXJ2eH-RSxTlhUxo4olsqSEKy3TkiRpqFpDkVQJTwsMTFKtKuAaNM8TyBNNipxCziGDROdsJ_q4mju33a9eOS8a4-TwlFZ1vRNZxouCsiKA7_8BZ11v2-BNkCJJGM0zHiC-gqTtnLNKi7k1DdilIFgMuYqZGOITQ3xiyFU85SoWQfp2Pb8vG1X9Fa6DDMCHNQBOQq3DP0vjNhwlJCWcJoH7suIeTa2W_21AnB8f3YZd0McrvXFeLTZ6sD9FlrM8Fd--nojJd_rjNLs5FyTw71a8hk7A1AZPd7cUE4ZJyllwz_4AaD7YHw</recordid><startdate>2009</startdate><enddate>2009</enddate><creator>Zhang, Z.C</creator><creator>Lian, B</creator><creator>Huang, D.M</creator><creator>Cui, F.J</creator><general>Blackwell Publishing Inc</general><general>Wiley</general><general>Wiley Subscription Services, Inc</general><scope>FBQ</scope><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>7QR</scope><scope>7ST</scope><scope>7T7</scope><scope>7U7</scope><scope>8FD</scope><scope>C1K</scope><scope>F28</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope><scope>SOI</scope><scope>7X8</scope></search><sort><creationdate>2009</creationdate><title>Compare Activities on Regulating Lipid-Metabolism and Reducing Oxidative Stress of Diabetic Rats of Tremella Aurantialba Broth's Extract (TBE) with Its Mycelia Polysaccharides (TMP)</title><author>Zhang, Z.C ; Lian, B ; Huang, D.M ; Cui, F.J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5369-32e34cb218efc5b145efcffa94d48590a3c2feda8faf874a74f1972a78a6a4f73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Agaricales - chemistry</topic><topic>animal models</topic><topic>Animals</topic><topic>antioxidant activity</topic><topic>Biological and medical sciences</topic><topic>blood glucose</topic><topic>Blood Glucose - drug effects</topic><topic>blood lipids</topic><topic>Carbohydrates</topic><topic>catalase</topic><topic>cholesterol</topic><topic>Cholesterol - blood</topic><topic>Diabetes</topic><topic>diabetes mellitus</topic><topic>Diabetes Mellitus, Experimental - drug therapy</topic><topic>diet-related diseases</topic><topic>Food industries</topic><topic>Food science</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Fungi</topic><topic>Glucose</topic><topic>glutathione reductase (NADPH)</topic><topic>Glutathione Reductase - metabolism</topic><topic>human diseases</topic><topic>lipid metabolism</topic><topic>Lipid Metabolism - drug effects</topic><topic>Lipids</topic><topic>malondialdehyde</topic><topic>Malondialdehyde - metabolism</topic><topic>medicinal properties</topic><topic>Metabolism</topic><topic>mycelium</topic><topic>Mycelium - chemistry</topic><topic>oxidative press</topic><topic>oxidative stress</topic><topic>Oxidative Stress - drug effects</topic><topic>plant extracts</topic><topic>polysaccharides</topic><topic>Polysaccharides - pharmacology</topic><topic>Random Allocation</topic><topic>Rats</topic><topic>Rats, Wistar</topic><topic>Rodents</topic><topic>Saponins - pharmacology</topic><topic>superoxide dismutase</topic><topic>Superoxide Dismutase - metabolism</topic><topic>Tremella</topic><topic>Tremella aurantialba</topic><topic>triacylglycerols</topic><topic>Triglycerides - blood</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zhang, Z.C</creatorcontrib><creatorcontrib>Lian, B</creatorcontrib><creatorcontrib>Huang, D.M</creatorcontrib><creatorcontrib>Cui, F.J</creatorcontrib><collection>AGRIS</collection><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Environment Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Toxicology Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ANTE: Abstracts in New Technology & Engineering</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>Environment Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of food science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zhang, Z.C</au><au>Lian, B</au><au>Huang, D.M</au><au>Cui, F.J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Compare Activities on Regulating Lipid-Metabolism and Reducing Oxidative Stress of Diabetic Rats of Tremella Aurantialba Broth's Extract (TBE) with Its Mycelia Polysaccharides (TMP)</atitle><jtitle>Journal of food science</jtitle><addtitle>J Food Sci</addtitle><date>2009</date><risdate>2009</risdate><volume>74</volume><issue>1</issue><spage>H15</spage><epage>H21</epage><pages>H15-H21</pages><issn>0022-1147</issn><eissn>1750-3841</eissn><coden>JFDSAZ</coden><abstract>Abnormal lipid-metabolism and elevated oxidative stress are the familiar complications of diabetic mellitus. Regulated lipid-metabolism and decreased oxidative stress have become the key indices to cure diabetic complications. The activities of broth extract (TBE) and mycelia polysaccharides (TMP) of Tremella aurantialba, which is one of the best-known multipurpose medicinal fungi in China, were studied using alloxan-induced diabetic rats. TBE contains saponins, while TMP contains polysaccharides. Both TBE and TMP could reduce the blood glucose levels of diabetic rats; TBE had stronger abilities to reduce the levels of total cholesterol and total triglyceride in serum, those of malondialdehyde, and enhance the activities of superoxide dismutase and glutathione reductase in different tissues of diabetic rats (P < 0.01). TBE had slightly stronger abilities to enhance the total antioxidant capability, catalase, and glutathione peroxidase in different tissues of diabetic rats, but no significant difference was found between TBE and TMP groups. All these results indicated that TBE was more capable of regulating lipid-metabolism and decreasing oxidative stress.</abstract><cop>Malden, USA</cop><pub>Blackwell Publishing Inc</pub><pmid>19200097</pmid><doi>10.1111/j.1750-3841.2008.00989.x</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Journal of food science, 2009, Vol.74 (1), p.H15-H21 |
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| subjects | Agaricales - chemistry animal models Animals antioxidant activity Biological and medical sciences blood glucose Blood Glucose - drug effects blood lipids Carbohydrates catalase cholesterol Cholesterol - blood Diabetes diabetes mellitus Diabetes Mellitus, Experimental - drug therapy diet-related diseases Food industries Food science Fundamental and applied biological sciences. Psychology Fungi Glucose glutathione reductase (NADPH) Glutathione Reductase - metabolism human diseases lipid metabolism Lipid Metabolism - drug effects Lipids malondialdehyde Malondialdehyde - metabolism medicinal properties Metabolism mycelium Mycelium - chemistry oxidative press oxidative stress Oxidative Stress - drug effects plant extracts polysaccharides Polysaccharides - pharmacology Random Allocation Rats Rats, Wistar Rodents Saponins - pharmacology superoxide dismutase Superoxide Dismutase - metabolism Tremella Tremella aurantialba triacylglycerols Triglycerides - blood |
| title | Compare Activities on Regulating Lipid-Metabolism and Reducing Oxidative Stress of Diabetic Rats of Tremella Aurantialba Broth's Extract (TBE) with Its Mycelia Polysaccharides (TMP) |
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