Remifentanil-propofol analgo-sedation shortens duration of ventilation and length of ICU stay compared to a conventional regimen: a centre randomised, cross-over, open-label study in the Netherlands

Objective Compare duration of mechanical ventilation (MV), weaning time, ICU-LOS (ICU-LOS), efficacy and safety of remifentanil-based regimen with conventional sedation and analgesia. Design Centre randomised, open-label, crossover, ‘real-life’ study. Setting 15 Dutch hospitals. Patients Adult medic...

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Veröffentlicht in:	Intensive care medicine 2009-02, Vol.35 (2), p.291-298
Hauptverfasser:	Rozendaal, F. Willem, Spronk, Peter E., Snellen, Ferdinand F., Schoen, Adri, van Zanten, Arthur R. H., Foudraine, Norbert A., Mulder, Paul G. H., Bakker, Jan
Format:	Artikel
Sprache:	eng
Schlagworte:	Analgesics Anesthesia Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Anesthesiology Biological and medical sciences Critical Care Medicine Cross-Over Studies Emergency and intensive respiratory care Emergency Medicine Female Fentanyl Humans Hypnotics and Sedatives - administration & dosage Intensive Intensive care Intensive care medicine Male Medical sciences Medicine Medicine & Public Health Metabolism Metabolites Middle Aged Morphine Narcotics Netherlands - epidemiology Original Pain Medicine Patients Pediatrics Pharmacokinetics Piperidines - administration & dosage Pneumology/Respiratory System Propofol - administration & dosage Psychomotor Agitation - epidemiology Psychomotor Agitation - prevention & control Respiration, Artificial - methods Respiratory Insufficiency - epidemiology Respiratory Insufficiency - therapy Ventilator Weaning - statistics & numerical data Ventilators Weaning
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