Sleep and non-invasive ventilation in patients with chronic respiratory insufficiency
Objective Noninvasive ventilation with pressure support (NIV-PS) therapy can augment ventilation; however, such therapy is fixed and may not adapt to varied patient needs. We tested the hypothesis that in patients with chronic respiratory insufficiency, a newer mode of ventilation [averaged volume a...
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| Veröffentlicht in: | Intensive care medicine 2009-02, Vol.35 (2), p.306-313, Article 306 |
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| creator | Ambrogio, Cristina Lowman, Xazmin Kuo, Ming Malo, Joshua Prasad, Anil R. Parthasarathy, Sairam |
| description | Objective
Noninvasive ventilation with pressure support (NIV-PS) therapy can augment ventilation; however, such therapy is fixed and may not adapt to varied patient needs. We tested the hypothesis that in patients with chronic respiratory insufficiency, a newer mode of ventilation [averaged volume assured pressure support (AVAPS)] and lateral decubitus position were associated with better sleep efficiency than NIV-PS and supine position. Our secondary aim was to assess the effect of mode of ventilation, body position, and sleep–wakefulness state on minute ventilation
in the same patients.
Design
Single-blind, randomized, cross-over, prospective study.
Setting
Academic institution.
Patients and participants
Twenty-eight patients.
Interventions
NIV-PS or AVAPS therapy.
Measurements and results
Three sleep studies were performed in each patient; prescription validation night, AVAPS or NIV-PS, and crossover to alternate mode. Sleep was not different between AVAPS and NIV-PS. Supine body position was associated with worse sleep efficiency than lateral decubitus position (77.9 ± 22.9 and 85.2 ± 10.5%;
P
= 0.04).
was lower during stage 2 NREM and REM sleep than during wakefulness (
P
|
| doi_str_mv | 10.1007/s00134-008-1276-4 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_66897881</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2914222791</sourcerecordid><originalsourceid>FETCH-LOGICAL-c443t-c8f5bd1b983fb8abe6fefcede395dea6896b49d35d70f3a00d5873aa4c3bf12d3</originalsourceid><addsrcrecordid>eNp10F1rFDEUBuAgit1Wf4A3MiB6NzYnX5O5lKJWKPTC9jpkkhObMpsZk5mV_fdm2UVF6FW-nnNyeAl5A_QjUNpdFkqBi5ZS3QLrVCuekQ0IzuqJ6-dkQ7lgrVCCnZHzUh6r7pSEl-QMdNdLJuWG3H8fEefGJt-kKbUx7WyJO2x2mJY42iVOqYmpmeuu3pTmV1weGveQpxRdk7HMMdtlyvuKyhpCdJW5_SvyItix4OvTekHuv3y-u7pub26_frv6dNM6IfjSOh3k4GHoNQ-DtgOqgMGhR95Lj1bpXg2i91z6jgZuKfVSd9xa4fgQgHl-QT4c-855-rliWcw2FofjaBNOazGqtui0hgrf_QcfpzWnOpsBDrLXwKSoCo7K5amUjMHMOW5t3hug5pC4OSZuauLmkLg51Lw9dV6HLfq_FaeIK3h_ArY4O4Zsk4vlj2MATGl1cOzoSn1KPzD_M-KTv_8GKIqaWQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1315981254</pqid></control><display><type>article</type><title>Sleep and non-invasive ventilation in patients with chronic respiratory insufficiency</title><source>MEDLINE</source><source>SpringerLink Journals - AutoHoldings</source><creator>Ambrogio, Cristina ; Lowman, Xazmin ; Kuo, Ming ; Malo, Joshua ; Prasad, Anil R. ; Parthasarathy, Sairam</creator><creatorcontrib>Ambrogio, Cristina ; Lowman, Xazmin ; Kuo, Ming ; Malo, Joshua ; Prasad, Anil R. ; Parthasarathy, Sairam</creatorcontrib><description>Objective
Noninvasive ventilation with pressure support (NIV-PS) therapy can augment ventilation; however, such therapy is fixed and may not adapt to varied patient needs. We tested the hypothesis that in patients with chronic respiratory insufficiency, a newer mode of ventilation [averaged volume assured pressure support (AVAPS)] and lateral decubitus position were associated with better sleep efficiency than NIV-PS and supine position. Our secondary aim was to assess the effect of mode of ventilation, body position, and sleep–wakefulness state on minute ventilation
in the same patients.
Design
Single-blind, randomized, cross-over, prospective study.
Setting
Academic institution.
Patients and participants
Twenty-eight patients.
Interventions
NIV-PS or AVAPS therapy.
Measurements and results
Three sleep studies were performed in each patient; prescription validation night, AVAPS or NIV-PS, and crossover to alternate mode. Sleep was not different between AVAPS and NIV-PS. Supine body position was associated with worse sleep efficiency than lateral decubitus position (77.9 ± 22.9 and 85.2 ± 10.5%;
P
= 0.04).
was lower during stage 2 NREM and REM sleep than during wakefulness (
P
< 0.0001); was lower during NIV-PS than AVAPS (
P
= 0.029); tended to be lower with greater body mass index (
P
= 0.07), but was not influenced by body position.
Conclusions
In patients with chronic respiratory insufficiency, supine position was associated with worse sleep efficiency than the lateral decubitus position. AVAPS was comparable to NIV-PS therapy with regard to sleep, but statistically greater
during AVAPS than NIV-PS of unclear significance was observed.
was determined by sleep–wakefulness state, body mass index, and mode of therapy.</description><identifier>ISSN: 0342-4642</identifier><identifier>EISSN: 1432-1238</identifier><identifier>DOI: 10.1007/s00134-008-1276-4</identifier><identifier>PMID: 18795255</identifier><identifier>CODEN: ICMED9</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer-Verlag</publisher><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Anesthesiology ; Biological and medical sciences ; Body Mass Index ; Chronic Disease ; Chronic obstructive pulmonary disease ; Critical Care Medicine ; Cross-Over Studies ; Emergency and intensive respiratory care ; Emergency Medicine ; Female ; Humans ; Hypotheses ; Hypoventilation ; Hypoventilation - epidemiology ; Intensive ; Intensive care medicine ; Male ; Medical sciences ; Medicine ; Medicine & Public Health ; Middle Aged ; Obesity ; Obesity - epidemiology ; Original ; Pain Medicine ; Patients ; Pediatrics ; Pneumology/Respiratory System ; Polysomnography ; Positive-Pressure Respiration - methods ; Respiration ; Respiratory failure ; Respiratory Insufficiency - epidemiology ; Respiratory Insufficiency - therapy ; Sleep ; Snoring - diagnosis ; Snoring - epidemiology ; Ventilators</subject><ispartof>Intensive care medicine, 2009-02, Vol.35 (2), p.306-313, Article 306</ispartof><rights>Springer-Verlag 2008</rights><rights>2009 INIST-CNRS</rights><rights>Springer-Verlag 2009</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c443t-c8f5bd1b983fb8abe6fefcede395dea6896b49d35d70f3a00d5873aa4c3bf12d3</citedby><cites>FETCH-LOGICAL-c443t-c8f5bd1b983fb8abe6fefcede395dea6896b49d35d70f3a00d5873aa4c3bf12d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00134-008-1276-4$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00134-008-1276-4$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27903,27904,41467,42536,51297</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=21126865$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18795255$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ambrogio, Cristina</creatorcontrib><creatorcontrib>Lowman, Xazmin</creatorcontrib><creatorcontrib>Kuo, Ming</creatorcontrib><creatorcontrib>Malo, Joshua</creatorcontrib><creatorcontrib>Prasad, Anil R.</creatorcontrib><creatorcontrib>Parthasarathy, Sairam</creatorcontrib><title>Sleep and non-invasive ventilation in patients with chronic respiratory insufficiency</title><title>Intensive care medicine</title><addtitle>Intensive Care Med</addtitle><addtitle>Intensive Care Med</addtitle><description>Objective
Noninvasive ventilation with pressure support (NIV-PS) therapy can augment ventilation; however, such therapy is fixed and may not adapt to varied patient needs. We tested the hypothesis that in patients with chronic respiratory insufficiency, a newer mode of ventilation [averaged volume assured pressure support (AVAPS)] and lateral decubitus position were associated with better sleep efficiency than NIV-PS and supine position. Our secondary aim was to assess the effect of mode of ventilation, body position, and sleep–wakefulness state on minute ventilation
in the same patients.
Design
Single-blind, randomized, cross-over, prospective study.
Setting
Academic institution.
Patients and participants
Twenty-eight patients.
Interventions
NIV-PS or AVAPS therapy.
Measurements and results
Three sleep studies were performed in each patient; prescription validation night, AVAPS or NIV-PS, and crossover to alternate mode. Sleep was not different between AVAPS and NIV-PS. Supine body position was associated with worse sleep efficiency than lateral decubitus position (77.9 ± 22.9 and 85.2 ± 10.5%;
P
= 0.04).
was lower during stage 2 NREM and REM sleep than during wakefulness (
P
< 0.0001); was lower during NIV-PS than AVAPS (
P
= 0.029); tended to be lower with greater body mass index (
P
= 0.07), but was not influenced by body position.
Conclusions
In patients with chronic respiratory insufficiency, supine position was associated with worse sleep efficiency than the lateral decubitus position. AVAPS was comparable to NIV-PS therapy with regard to sleep, but statistically greater
during AVAPS than NIV-PS of unclear significance was observed.
was determined by sleep–wakefulness state, body mass index, and mode of therapy.</description><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Anesthesiology</subject><subject>Biological and medical sciences</subject><subject>Body Mass Index</subject><subject>Chronic Disease</subject><subject>Chronic obstructive pulmonary disease</subject><subject>Critical Care Medicine</subject><subject>Cross-Over Studies</subject><subject>Emergency and intensive respiratory care</subject><subject>Emergency Medicine</subject><subject>Female</subject><subject>Humans</subject><subject>Hypotheses</subject><subject>Hypoventilation</subject><subject>Hypoventilation - epidemiology</subject><subject>Intensive</subject><subject>Intensive care medicine</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Obesity</subject><subject>Obesity - epidemiology</subject><subject>Original</subject><subject>Pain Medicine</subject><subject>Patients</subject><subject>Pediatrics</subject><subject>Pneumology/Respiratory System</subject><subject>Polysomnography</subject><subject>Positive-Pressure Respiration - methods</subject><subject>Respiration</subject><subject>Respiratory failure</subject><subject>Respiratory Insufficiency - epidemiology</subject><subject>Respiratory Insufficiency - therapy</subject><subject>Sleep</subject><subject>Snoring - diagnosis</subject><subject>Snoring - epidemiology</subject><subject>Ventilators</subject><issn>0342-4642</issn><issn>1432-1238</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp10F1rFDEUBuAgit1Wf4A3MiB6NzYnX5O5lKJWKPTC9jpkkhObMpsZk5mV_fdm2UVF6FW-nnNyeAl5A_QjUNpdFkqBi5ZS3QLrVCuekQ0IzuqJ6-dkQ7lgrVCCnZHzUh6r7pSEl-QMdNdLJuWG3H8fEefGJt-kKbUx7WyJO2x2mJY42iVOqYmpmeuu3pTmV1weGveQpxRdk7HMMdtlyvuKyhpCdJW5_SvyItix4OvTekHuv3y-u7pub26_frv6dNM6IfjSOh3k4GHoNQ-DtgOqgMGhR95Lj1bpXg2i91z6jgZuKfVSd9xa4fgQgHl-QT4c-855-rliWcw2FofjaBNOazGqtui0hgrf_QcfpzWnOpsBDrLXwKSoCo7K5amUjMHMOW5t3hug5pC4OSZuauLmkLg51Lw9dV6HLfq_FaeIK3h_ArY4O4Zsk4vlj2MATGl1cOzoSn1KPzD_M-KTv_8GKIqaWQ</recordid><startdate>20090201</startdate><enddate>20090201</enddate><creator>Ambrogio, Cristina</creator><creator>Lowman, Xazmin</creator><creator>Kuo, Ming</creator><creator>Malo, Joshua</creator><creator>Prasad, Anil R.</creator><creator>Parthasarathy, Sairam</creator><general>Springer-Verlag</general><general>Springer</general><general>Springer Nature B.V</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M7Z</scope><scope>NAPCQ</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20090201</creationdate><title>Sleep and non-invasive ventilation in patients with chronic respiratory insufficiency</title><author>Ambrogio, Cristina ; Lowman, Xazmin ; Kuo, Ming ; Malo, Joshua ; Prasad, Anil R. ; Parthasarathy, Sairam</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c443t-c8f5bd1b983fb8abe6fefcede395dea6896b49d35d70f3a00d5873aa4c3bf12d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Anesthesiology</topic><topic>Biological and medical sciences</topic><topic>Body Mass Index</topic><topic>Chronic Disease</topic><topic>Chronic obstructive pulmonary disease</topic><topic>Critical Care Medicine</topic><topic>Cross-Over Studies</topic><topic>Emergency and intensive respiratory care</topic><topic>Emergency Medicine</topic><topic>Female</topic><topic>Humans</topic><topic>Hypotheses</topic><topic>Hypoventilation</topic><topic>Hypoventilation - epidemiology</topic><topic>Intensive</topic><topic>Intensive care medicine</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Obesity</topic><topic>Obesity - epidemiology</topic><topic>Original</topic><topic>Pain Medicine</topic><topic>Patients</topic><topic>Pediatrics</topic><topic>Pneumology/Respiratory System</topic><topic>Polysomnography</topic><topic>Positive-Pressure Respiration - methods</topic><topic>Respiration</topic><topic>Respiratory failure</topic><topic>Respiratory Insufficiency - epidemiology</topic><topic>Respiratory Insufficiency - therapy</topic><topic>Sleep</topic><topic>Snoring - diagnosis</topic><topic>Snoring - epidemiology</topic><topic>Ventilators</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ambrogio, Cristina</creatorcontrib><creatorcontrib>Lowman, Xazmin</creatorcontrib><creatorcontrib>Kuo, Ming</creatorcontrib><creatorcontrib>Malo, Joshua</creatorcontrib><creatorcontrib>Prasad, Anil R.</creatorcontrib><creatorcontrib>Parthasarathy, Sairam</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biochemistry Abstracts 1</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Intensive care medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ambrogio, Cristina</au><au>Lowman, Xazmin</au><au>Kuo, Ming</au><au>Malo, Joshua</au><au>Prasad, Anil R.</au><au>Parthasarathy, Sairam</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Sleep and non-invasive ventilation in patients with chronic respiratory insufficiency</atitle><jtitle>Intensive care medicine</jtitle><stitle>Intensive Care Med</stitle><addtitle>Intensive Care Med</addtitle><date>2009-02-01</date><risdate>2009</risdate><volume>35</volume><issue>2</issue><spage>306</spage><epage>313</epage><pages>306-313</pages><artnum>306</artnum><issn>0342-4642</issn><eissn>1432-1238</eissn><coden>ICMED9</coden><abstract>Objective
Noninvasive ventilation with pressure support (NIV-PS) therapy can augment ventilation; however, such therapy is fixed and may not adapt to varied patient needs. We tested the hypothesis that in patients with chronic respiratory insufficiency, a newer mode of ventilation [averaged volume assured pressure support (AVAPS)] and lateral decubitus position were associated with better sleep efficiency than NIV-PS and supine position. Our secondary aim was to assess the effect of mode of ventilation, body position, and sleep–wakefulness state on minute ventilation
in the same patients.
Design
Single-blind, randomized, cross-over, prospective study.
Setting
Academic institution.
Patients and participants
Twenty-eight patients.
Interventions
NIV-PS or AVAPS therapy.
Measurements and results
Three sleep studies were performed in each patient; prescription validation night, AVAPS or NIV-PS, and crossover to alternate mode. Sleep was not different between AVAPS and NIV-PS. Supine body position was associated with worse sleep efficiency than lateral decubitus position (77.9 ± 22.9 and 85.2 ± 10.5%;
P
= 0.04).
was lower during stage 2 NREM and REM sleep than during wakefulness (
P
< 0.0001); was lower during NIV-PS than AVAPS (
P
= 0.029); tended to be lower with greater body mass index (
P
= 0.07), but was not influenced by body position.
Conclusions
In patients with chronic respiratory insufficiency, supine position was associated with worse sleep efficiency than the lateral decubitus position. AVAPS was comparable to NIV-PS therapy with regard to sleep, but statistically greater
during AVAPS than NIV-PS of unclear significance was observed.
was determined by sleep–wakefulness state, body mass index, and mode of therapy.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer-Verlag</pub><pmid>18795255</pmid><doi>10.1007/s00134-008-1276-4</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
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| ispartof | Intensive care medicine, 2009-02, Vol.35 (2), p.306-313, Article 306 |
| issn | 0342-4642 1432-1238 |
| language | eng |
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| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Anesthesiology Biological and medical sciences Body Mass Index Chronic Disease Chronic obstructive pulmonary disease Critical Care Medicine Cross-Over Studies Emergency and intensive respiratory care Emergency Medicine Female Humans Hypotheses Hypoventilation Hypoventilation - epidemiology Intensive Intensive care medicine Male Medical sciences Medicine Medicine & Public Health Middle Aged Obesity Obesity - epidemiology Original Pain Medicine Patients Pediatrics Pneumology/Respiratory System Polysomnography Positive-Pressure Respiration - methods Respiration Respiratory failure Respiratory Insufficiency - epidemiology Respiratory Insufficiency - therapy Sleep Snoring - diagnosis Snoring - epidemiology Ventilators |
| title | Sleep and non-invasive ventilation in patients with chronic respiratory insufficiency |
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