Monitoring and control of Gluconacetobacter xylinus fed-batch cultures using in situ mid-IR spectroscopy

A partial least-squares calibration model, relating mid-infrared spectral features with fructose, ethanol, acetate, gluconacetan, phosphate and ammonium concentrations has been designed to monitor and control cultivations of Gluconacetobacter xylinus and production of gluconacetan, a food grade exop...

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Veröffentlicht in:	Journal of biotechnology 2004-09, Vol.113 (1), p.231-245
Hauptverfasser:	Kornmann, Henri, Valentinotti, Sergio, Duboc, Philippe, Marison, Ian, von Stockar, Urs
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms batch fermentation Biological and medical sciences Bioreactors Biotechnology Biotechnology - instrumentation Biotechnology - methods Calibration carbohydrate metabolism Closed-loop control Culture Media Ethanol - metabolism Exopolysaccharide production exopolysaccharides food additives Fundamental and applied biological sciences. Psychology gluconacetan Gluconacetan production Gluconacetobacter xylinus Gluconacetobacter xylinus - growth & development Gluconacetobacter xylinus - metabolism Gluconacetobactor xylinus Industrial Microbiology - instrumentation Industrial Microbiology - methods infrared spectroscopy On-line MIR spectroscopy polysaccharides Spectrophotometry, Infrared - methods thickeners
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