Transport across the blood-brain barrier: stereoselectivity and PET-tracers

This article reviews positron emission tomography (PET) studies of labeled enantiomers of different PET-tracers from the early 1980s. Comparative studies on stereoselective behavior of the transport of tracers across the blood-brain barrier (BBB) are discussed. Tracers are transported through the BB...

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Veröffentlicht in:	Molecular imaging and biology 2004-09, Vol.6 (5), p.306-318
Hauptverfasser:	Luurtsema, Gert, de Lange, Elizabeth C.M., Lammertsma, Adriaan A., Franssen, Eric J.F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acids - metabolism BBB Blood-brain barrier Blood-Brain Barrier - metabolism Blood-Brain Barrier - pathology Brain - diagnostic imaging Brain - metabolism Brain - pathology Hexoses - metabolism Humans PET Positron emission tomography Radioactive Tracers Radiography Stereoisomerism Stereoselectivity Tracers
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