Living with the Past: Evolution, Development, and Patterns of Disease
Epidemiological observations have led to the hypothesis that the risk of developing some chronic noncommunicable diseases in adulthood is influenced not only by genetic and adult life-style factors but also by environmental factors acting in early life. Research in evolutionary biology, developmenta...
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| Veröffentlicht in: | Science (American Association for the Advancement of Science) 2004-09, Vol.305 (5691), p.1733-1736 |
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| container_issue | 5691 |
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| creator | Gluckman, Peter D. Hanson, Mark A. |
| description | Epidemiological observations have led to the hypothesis that the risk of developing some chronic noncommunicable diseases in adulthood is influenced not only by genetic and adult life-style factors but also by environmental factors acting in early life. Research in evolutionary biology, developmental biology, and animal and human physiology provides support for this idea and suggests that environmental processes influencing the propensity to disease in adulthood operate during the periconceptual, fetal, and infant phases of life. This "developmental origins of health and disease" concept may have important biological, medical, and socioeconomic implications. |
| doi_str_mv | 10.1126/science.1095292 |
| format | Article |
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| ispartof | Science (American Association for the Advancement of Science), 2004-09, Vol.305 (5691), p.1733-1736 |
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| language | eng |
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| source | MEDLINE; JSTOR Archive Collection A-Z Listing; American Association for the Advancement of Science |
| subjects | Adolescents Adults Analysis. Health state Animals Biological and medical sciences Biological Evolution Birth Weight Body Weight Causes of Chronic Disease Chronic diseases Cues Development and progression Developmental biology Diabetes Disease - etiology Disease models Disease risk Disease Susceptibility Embryonic and Fetal Development Environment Environmental disorders Environmental impact Environmental Influences Environmental quality Epidemiology Evidence Evolution Female Fetal diseases Fetus General aspects Humans Impact analysis Infant, Newborn Life Style Medical disorders Medical genetics Medical sciences Nutritional Physiological Phenomena Obesity Pathology Physiology Pregnancy Prenatal Exposure Delayed Effects Public health. Hygiene Public health. Hygiene-occupational medicine Reviews Risk Factors Young Children |
| title | Living with the Past: Evolution, Development, and Patterns of Disease |
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