Mitogen-activated protein kinase 3/mitogen-activated protein kinase 1 activates apoptosis during testicular ischemia-reperfusion injury in a nuclear factor-kappaB-independent manner

Nuclear factor kappa-B (NF-kappaB), mitogen-activated protein kinase3/MAPK1 and MAPK8 are involved in testicular ischemia reperfusion injury (testicular-I/R). NF-kappaB knock-out mice (KO) subjected to testicular-I/R have a reduced testicular damage, blunted MAPK8 activation and enhanced MAPK3/MAPK1...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	European journal of pharmacology 2009-02, Vol.604 (1-3), p.27-35
Hauptverfasser:	Minutoli, Letteria, Antonuccio, Pietro, Polito, Francesca, Bitto, Alessandra, Squadrito, Francesco, Di Stefano, Vincenzo, Nicotina, Piero Antonio, Fazzari, Carmine, Maisano, Daniele, Romeo, Carmelo, Altavilla, Domenica
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Enzyme Inhibitors - pharmacology Flavonoids - pharmacology Male Mice Mice, Knockout Mitogen-Activated Protein Kinase 1 - antagonists & inhibitors Mitogen-Activated Protein Kinase 1 - biosynthesis Mitogen-Activated Protein Kinase 3 - antagonists & inhibitors Mitogen-Activated Protein Kinase 3 - biosynthesis NF-kappa B - genetics NF-kappa B - metabolism Reperfusion Injury - enzymology Reperfusion Injury - metabolism Reperfusion Injury - pathology Testis - blood supply Testis - enzymology Testis - metabolism Testis - pathology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!