Insertion (4;11)(q27;q24q21) in a patient with essential thrombocythemia with progression to myelofibrosis

We report a case of essential thrombocythemia (ET) in a 39-year-old woman who developed myelofibrosis at follow-up. The cytogenetic and fluorescence in situ hybridization analyses revealed a pathologic clone with the following previously unreported karyotype: 46,XX,ins(4;11)(q27;q24q21). We cannot c...

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Veröffentlicht in:	Cancer genetics and cytogenetics 2004-10, Vol.154 (1), p.72-76
Hauptverfasser:	Gargallo, Patricia, Hagemeijer, Anne, Vassallu, Patricia, Kornblihtt, Laura, Heller, Paula, Molinas, Felisa, Larripa, Irene
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Bone Marrow - pathology Chromosome Inversion Chromosomes, Human, Pair 11 Chromosomes, Human, Pair 4 Disease Progression Female Gene Rearrangement Humans In Situ Hybridization, Fluorescence Primary Myelofibrosis - genetics Primary Myelofibrosis - pathology Thrombocythemia, Essential - genetics Thrombocythemia, Essential - pathology
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