Emergence of adefovir-resistant mutants after reversion to YMDD wild-type in lamivudine-resistant patients receiving adefovir monotherapy

Background:  To evaluate the effect of reversion to YMDD wild‐type on emergence of adefovir (ADV)‐resistant mutation and antiviral activity of ADV in lamivudine (LAM)‐ resistant patients. Methods:  We determined YMDD mutations and ADV‐resistant mutations before and every 3 months during ADV monother...

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Veröffentlicht in:Journal of gastroenterology and hepatology 2009-01, Vol.24 (1), p.49-54
Hauptverfasser: Kwon, Hyeok Choon, Cheong, Jae Youn, Cho, Sung Won, Choi, Jae Myoung, Hong, Sun Pyo, Kim, Soo-Ok, Yoo, Wang Don
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Sprache:eng
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