Factor XIII-A subunit Val34Leu polymorphism is associated with the risk of thrombosis in patients with antiphospholipid antibodies and high fibrinogen levels

Summary Recent reports have described the factor XIII A subunit (FXIII-A) Val34Leu polymorphism as a protective factor against venous and arterial thrombosis. The aim of this study was to investigate the association between the FXIII-A Val34Leu polymorphism, its interaction with fibrinogen concentra...

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Veröffentlicht in:	Thrombosis and haemostasis 2009-02, Vol.101 (2), p.312-316
Hauptverfasser:	Red, Gloria de la, Tàssies, Dolores, Espinosa, Gerard, Monteagudo, Joan, Bové, Albert, Plaza, Joan, Cervera, Ricard, Reverter, Joan-Carles
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antiphospholipid antibodies Antiphospholipid Syndrome - blood Antiphospholipid Syndrome - complications Antiphospholipid Syndrome - genetics Blood Coagulation, Fibrinolysis and Cellular Haemostasis Case-Control Studies Factor XIII - genetics Factor XIII polymorphism Female fibrinogen Fibrinogen - analysis Gene Frequency Genetic Predisposition to Disease Humans Leucine Male Odds Ratio Polymorphism, Genetic Protein Subunits Risk Assessment Risk Factors thrombosis Thrombosis - blood Thrombosis - genetics Up-Regulation Valine
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