Identification of hydroxyl radicals after UV irradiation of aqueous extracts of cigarette smoke and evaluation of urinary 8-OHdG in smokers

The role of oxidative stress in tobacco smoke damage was examined using a combination of in vitro and in vivo approaches. Aqueous extracts of cigarette smoke were irradiated with UV and hydroxyl radical generation was evaluated by electron spin resonance (ESR). The spectra obtained revealed spin add...

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Veröffentlicht in:	Asian Pacific journal of cancer prevention : APJCP 2004-07, Vol.5 (3), p.279-283
Hauptverfasser:	Yatsuzuka, Miki, Tazawa, Kenji, Yasuda, Tomomi, Yoshii, Miho, Ogawa, Kouhei, Wada, Shigeto
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants - pharmacology Ascorbic Acid - pharmacology Deoxyguanosine - analogs & derivatives Deoxyguanosine - urine DNA Damage Electron Spin Resonance Spectroscopy Free Radicals - analysis Humans Oxidative Stress Smoking - adverse effects Ultraviolet Rays
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