Enrichment of the thymoquinone content in volatile oil from Satureja montana using supercritical fluid extraction
Supercritical fluid extraction (SFE) of the volatile oil from Satureja montana L. was performed under different conditions of pressure (90 and 100 bar), temperature (40 and 50°C), mean particle sizes (0.4, 0.6 and 0.8 mm) and CO₂ flow rate (0.8, 1.1 and 1.3 kg/h) to understand the influence of these...
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| Veröffentlicht in: | Journal of separation science 2009, Vol.32 (2), p.328-334 |
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| creator | Grosso, Clara Figueiredo, Ana Cristina Burillo, Jesus Mainar, Ana M Urieta, José S Barroso, José G Coelho, José A Palavra, António M.F |
| description | Supercritical fluid extraction (SFE) of the volatile oil from Satureja montana L. was performed under different conditions of pressure (90 and 100 bar), temperature (40 and 50°C), mean particle sizes (0.4, 0.6 and 0.8 mm) and CO₂ flow rate (0.8, 1.1 and 1.3 kg/h) to understand the influence of these parameters on the composition and yield of this oil. The results were compared with those obtained for the essential oil isolated by hydrodistillation (HD). The volatile and the essential oil were analysed by GC and GC-MS. The main compounds are carvacrol (52.2-62.0% for HD vs. 41.7-64.5% for SFE), thymol (8.6-11.0% for HD vs. 6.0-11.3% for SFE), p-cymene (6.9-12.8% for HD vs. 6.0-17.8% for SFE), γ-terpinene (6.4-9.4% for HD vs. 2.3-6.0% for SFE) and β-bisabolene (2.0-2.7% for HD vs. 2.2-3.5% for SFE). The major difference between SFE and HD was the relative amount of thymoquinone, an oxygenated monoterpene with important biological activities, which can be ten-fold higher in volatile oil (1.6-3.0 for SFE vs. 0.2% for HD). The morphology of the glandular trichomes of S. montana and the effect of the grinding process on them was also evaluated by SEM. |
| doi_str_mv | 10.1002/jssc.200800490 |
| format | Article |
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The results were compared with those obtained for the essential oil isolated by hydrodistillation (HD). The volatile and the essential oil were analysed by GC and GC-MS. The main compounds are carvacrol (52.2-62.0% for HD vs. 41.7-64.5% for SFE), thymol (8.6-11.0% for HD vs. 6.0-11.3% for SFE), p-cymene (6.9-12.8% for HD vs. 6.0-17.8% for SFE), γ-terpinene (6.4-9.4% for HD vs. 2.3-6.0% for SFE) and β-bisabolene (2.0-2.7% for HD vs. 2.2-3.5% for SFE). The major difference between SFE and HD was the relative amount of thymoquinone, an oxygenated monoterpene with important biological activities, which can be ten-fold higher in volatile oil (1.6-3.0 for SFE vs. 0.2% for HD). The morphology of the glandular trichomes of S. montana and the effect of the grinding process on them was also evaluated by SEM.</description><identifier>ISSN: 1615-9306</identifier><identifier>EISSN: 1615-9314</identifier><identifier>DOI: 10.1002/jssc.200800490</identifier><identifier>PMID: 19156634</identifier><language>eng</language><publisher>Weinheim: Wiley-VCH Verlag</publisher><subject>Applied sciences ; Aroma and flavouring agent industries ; Benzoquinones - isolation & purification ; Biological and medical sciences ; Carbon Dioxide - chemistry ; Chemical industry and chemicals ; Chromatography, Supercritical Fluid - methods ; Essential oils, perfumes ; Exact sciences and technology ; Food industries ; Fundamental and applied biological sciences. Psychology ; General pharmacology ; Hydrodistillation ; Medical sciences ; Microscopy, Electron, Scanning ; Oils, Volatile - chemistry ; Particle Size ; Pharmacognosy. Homeopathy. Health food ; Pharmacology. Drug treatments ; Pressure ; Satureja - chemistry ; Satureja - ultrastructure ; Satureja montana ; Supercritical fluid extraction ; Temperature ; Thymoquinone ; Volatiles ; Washing products. Cosmetics and toiletries. Perfumes</subject><ispartof>Journal of separation science, 2009, Vol.32 (2), p.328-334</ispartof><rights>Copyright © 2009 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim</rights><rights>2009 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3810-9cbaab1980b0bd1e5098901a6a55df46108e3396853e517361813b79f8aef0963</citedby><cites>FETCH-LOGICAL-c3810-9cbaab1980b0bd1e5098901a6a55df46108e3396853e517361813b79f8aef0963</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fjssc.200800490$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fjssc.200800490$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,4010,27900,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=21051501$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19156634$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Grosso, Clara</creatorcontrib><creatorcontrib>Figueiredo, Ana Cristina</creatorcontrib><creatorcontrib>Burillo, Jesus</creatorcontrib><creatorcontrib>Mainar, Ana M</creatorcontrib><creatorcontrib>Urieta, José S</creatorcontrib><creatorcontrib>Barroso, José G</creatorcontrib><creatorcontrib>Coelho, José A</creatorcontrib><creatorcontrib>Palavra, António M.F</creatorcontrib><title>Enrichment of the thymoquinone content in volatile oil from Satureja montana using supercritical fluid extraction</title><title>Journal of separation science</title><addtitle>J. Sep. Science</addtitle><description>Supercritical fluid extraction (SFE) of the volatile oil from Satureja montana L. was performed under different conditions of pressure (90 and 100 bar), temperature (40 and 50°C), mean particle sizes (0.4, 0.6 and 0.8 mm) and CO₂ flow rate (0.8, 1.1 and 1.3 kg/h) to understand the influence of these parameters on the composition and yield of this oil. The results were compared with those obtained for the essential oil isolated by hydrodistillation (HD). The volatile and the essential oil were analysed by GC and GC-MS. The main compounds are carvacrol (52.2-62.0% for HD vs. 41.7-64.5% for SFE), thymol (8.6-11.0% for HD vs. 6.0-11.3% for SFE), p-cymene (6.9-12.8% for HD vs. 6.0-17.8% for SFE), γ-terpinene (6.4-9.4% for HD vs. 2.3-6.0% for SFE) and β-bisabolene (2.0-2.7% for HD vs. 2.2-3.5% for SFE). The major difference between SFE and HD was the relative amount of thymoquinone, an oxygenated monoterpene with important biological activities, which can be ten-fold higher in volatile oil (1.6-3.0 for SFE vs. 0.2% for HD). The morphology of the glandular trichomes of S. montana and the effect of the grinding process on them was also evaluated by SEM.</description><subject>Applied sciences</subject><subject>Aroma and flavouring agent industries</subject><subject>Benzoquinones - isolation & purification</subject><subject>Biological and medical sciences</subject><subject>Carbon Dioxide - chemistry</subject><subject>Chemical industry and chemicals</subject><subject>Chromatography, Supercritical Fluid - methods</subject><subject>Essential oils, perfumes</subject><subject>Exact sciences and technology</subject><subject>Food industries</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>General pharmacology</subject><subject>Hydrodistillation</subject><subject>Medical sciences</subject><subject>Microscopy, Electron, Scanning</subject><subject>Oils, Volatile - chemistry</subject><subject>Particle Size</subject><subject>Pharmacognosy. Homeopathy. Health food</subject><subject>Pharmacology. Drug treatments</subject><subject>Pressure</subject><subject>Satureja - chemistry</subject><subject>Satureja - ultrastructure</subject><subject>Satureja montana</subject><subject>Supercritical fluid extraction</subject><subject>Temperature</subject><subject>Thymoquinone</subject><subject>Volatiles</subject><subject>Washing products. Cosmetics and toiletries. 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Psychology</topic><topic>General pharmacology</topic><topic>Hydrodistillation</topic><topic>Medical sciences</topic><topic>Microscopy, Electron, Scanning</topic><topic>Oils, Volatile - chemistry</topic><topic>Particle Size</topic><topic>Pharmacognosy. Homeopathy. Health food</topic><topic>Pharmacology. Drug treatments</topic><topic>Pressure</topic><topic>Satureja - chemistry</topic><topic>Satureja - ultrastructure</topic><topic>Satureja montana</topic><topic>Supercritical fluid extraction</topic><topic>Temperature</topic><topic>Thymoquinone</topic><topic>Volatiles</topic><topic>Washing products. Cosmetics and toiletries. Perfumes</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Grosso, Clara</creatorcontrib><creatorcontrib>Figueiredo, Ana Cristina</creatorcontrib><creatorcontrib>Burillo, Jesus</creatorcontrib><creatorcontrib>Mainar, Ana M</creatorcontrib><creatorcontrib>Urieta, José S</creatorcontrib><creatorcontrib>Barroso, José G</creatorcontrib><creatorcontrib>Coelho, José A</creatorcontrib><creatorcontrib>Palavra, António M.F</creatorcontrib><collection>AGRIS</collection><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Technology Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of separation science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Grosso, Clara</au><au>Figueiredo, Ana Cristina</au><au>Burillo, Jesus</au><au>Mainar, Ana M</au><au>Urieta, José S</au><au>Barroso, José G</au><au>Coelho, José A</au><au>Palavra, António M.F</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Enrichment of the thymoquinone content in volatile oil from Satureja montana using supercritical fluid extraction</atitle><jtitle>Journal of separation science</jtitle><addtitle>J. Sep. Science</addtitle><date>2009</date><risdate>2009</risdate><volume>32</volume><issue>2</issue><spage>328</spage><epage>334</epage><pages>328-334</pages><issn>1615-9306</issn><eissn>1615-9314</eissn><abstract>Supercritical fluid extraction (SFE) of the volatile oil from Satureja montana L. was performed under different conditions of pressure (90 and 100 bar), temperature (40 and 50°C), mean particle sizes (0.4, 0.6 and 0.8 mm) and CO₂ flow rate (0.8, 1.1 and 1.3 kg/h) to understand the influence of these parameters on the composition and yield of this oil. The results were compared with those obtained for the essential oil isolated by hydrodistillation (HD). The volatile and the essential oil were analysed by GC and GC-MS. The main compounds are carvacrol (52.2-62.0% for HD vs. 41.7-64.5% for SFE), thymol (8.6-11.0% for HD vs. 6.0-11.3% for SFE), p-cymene (6.9-12.8% for HD vs. 6.0-17.8% for SFE), γ-terpinene (6.4-9.4% for HD vs. 2.3-6.0% for SFE) and β-bisabolene (2.0-2.7% for HD vs. 2.2-3.5% for SFE). The major difference between SFE and HD was the relative amount of thymoquinone, an oxygenated monoterpene with important biological activities, which can be ten-fold higher in volatile oil (1.6-3.0 for SFE vs. 0.2% for HD). The morphology of the glandular trichomes of S. montana and the effect of the grinding process on them was also evaluated by SEM.</abstract><cop>Weinheim</cop><pub>Wiley-VCH Verlag</pub><pmid>19156634</pmid><doi>10.1002/jssc.200800490</doi><tpages>7</tpages></addata></record> |
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| subjects | Applied sciences Aroma and flavouring agent industries Benzoquinones - isolation & purification Biological and medical sciences Carbon Dioxide - chemistry Chemical industry and chemicals Chromatography, Supercritical Fluid - methods Essential oils, perfumes Exact sciences and technology Food industries Fundamental and applied biological sciences. Psychology General pharmacology Hydrodistillation Medical sciences Microscopy, Electron, Scanning Oils, Volatile - chemistry Particle Size Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Pressure Satureja - chemistry Satureja - ultrastructure Satureja montana Supercritical fluid extraction Temperature Thymoquinone Volatiles Washing products. Cosmetics and toiletries. Perfumes |
| title | Enrichment of the thymoquinone content in volatile oil from Satureja montana using supercritical fluid extraction |
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