Comparative analysis of NK cell subset distribution in normal and lymphoproliferative disease of granular lymphocyte conditions

We have characterized the heterogeneity of human blood NK cell subsets defined by expression of KIR, lectin like receptors and NK cell differentiation markers within a cohort of 51 healthy Caucasian individuals. High inter‐individual variability in cell surface expression of most NK cell markers is...

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Veröffentlicht in:	European journal of immunology 2004-10, Vol.34 (10), p.2930-2940
Hauptverfasser:	Pascal, Véronique, Schleinitz, Nicolas, Brunet, Corinne, Ravet, Sophie, Bonnet, Elodie, Lafarge, Xavier, Touinssi, Mhammed, Reviron, Denis, Viallard, Jean Francois, Moreau, Jean Francois, Déchanet‐Merville, Julie, Blanco, Patrick, Harlé, Jean Robert, Sampol, José, Vivier, Eric, Dignat‐George, Françoise, Paul, Pascale
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Biomarkers - analysis Blood Donors Female Flow Cytometry Genotype Humans Immunophenotyping Killer Cells, Natural - immunology Killer Cells, Natural - metabolism KIR Lymphocyte Subsets - immunology Lymphocyte Subsets - metabolism Lymphoproliferative Disorders - immunology Lymphoproliferative Disorders - metabolism Male Middle Aged Natural killer cells NK cell surface receptors NK‐lymphoproliferative disease of granular lymphocytes Polymerase Chain Reaction Receptors, Immunologic - metabolism Receptors, KIR Receptors, KIR2DL1 Receptors, KIR2DL2 Receptors, KIR2DL3 Receptors, KIR3DL1 Reference Values
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