Regulation of integrin function through conformational complexity: not simply a knee-jerk reaction?

Such diverse biological processes as the maintenance of tissue architecture and the regulation of cell migration are controlled through dynamic changes in integrin receptor conformation. Early analyses of the mechanisms of shape change by integrins led to the definition of three inter-convertible co...

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Veröffentlicht in:	Current opinion in cell biology 2004-10, Vol.16 (5), p.544-551
Hauptverfasser:	Mould, A Paul, Humphries, Martin J
Format:	Artikel
Sprache:	eng
Schlagworte:	Integrins - chemistry Integrins - metabolism Ligands Models, Molecular Protein Binding Protein Conformation Signal Transduction - physiology
Online-Zugang:	Volltext
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