Importation of visceral leishmaniasis in returning Romanian workers from Spain
Summary Background Over the past two decades visceral leishmaniasis cases and foci have increased in Romania, where the disease has also become a medical concern. The following study aimed to provide essential knowledge on early diagnosis and management of visceral leishmaniasis cases in Romania acq...
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Veröffentlicht in: | Travel medicine and infectious disease 2009-01, Vol.7 (1), p.35-39 |
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creator | Neghina, Raul Neghina, Adriana-Maria Merkler, Carmen Marincu, Iosif Moldovan, Roxana Iacobiciu, Ioan |
description | Summary Background Over the past two decades visceral leishmaniasis cases and foci have increased in Romania, where the disease has also become a medical concern. The following study aimed to provide essential knowledge on early diagnosis and management of visceral leishmaniasis cases in Romania acquired especially by traveling and working in the Mediterranean countries. Method Retrospective analysis of the medical records of the patients diagnosed with imported visceral leishmaniasis in a western Romanian county. Results Three patients with visceral leishmaniasis imported from Spain were admitted to hospital in Timisoara in 2005. Detailed case histories along with clinical and laboratory features are presented. In all the patients the final laboratory confirmation of the disease was by Giemsa-stained blood smears obtained by bone marrow biopsy. Conclusions Since 2004, many Romanian citizens left their homeland looking for a better job in the Mediterranean region. Unaware of the risks of outdoor labor in warm climatic conditions, they accepted to live and work in improper sanitary conditions. Late identification of the disease resulted mainly from failure of the physicians to diagnose and associate the syndrome with travel. |
doi_str_mv | 10.1016/j.tmaid.2008.10.002 |
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The following study aimed to provide essential knowledge on early diagnosis and management of visceral leishmaniasis cases in Romania acquired especially by traveling and working in the Mediterranean countries. Method Retrospective analysis of the medical records of the patients diagnosed with imported visceral leishmaniasis in a western Romanian county. Results Three patients with visceral leishmaniasis imported from Spain were admitted to hospital in Timisoara in 2005. Detailed case histories along with clinical and laboratory features are presented. In all the patients the final laboratory confirmation of the disease was by Giemsa-stained blood smears obtained by bone marrow biopsy. Conclusions Since 2004, many Romanian citizens left their homeland looking for a better job in the Mediterranean region. Unaware of the risks of outdoor labor in warm climatic conditions, they accepted to live and work in improper sanitary conditions. Late identification of the disease resulted mainly from failure of the physicians to diagnose and associate the syndrome with travel.</description><identifier>ISSN: 1477-8939</identifier><identifier>EISSN: 1873-0442</identifier><identifier>DOI: 10.1016/j.tmaid.2008.10.002</identifier><identifier>PMID: 19174299</identifier><language>eng</language><publisher>Netherlands: Elsevier Ltd</publisher><subject>Adult ; Amphotericin B - therapeutic use ; Antiprotozoal Agents - therapeutic use ; Bone marrow ; Bone marrow biopsy ; Climatic conditions ; Diagnosis, Differential ; Fatal Outcome ; Female ; Giemsa-stained blood smears ; Hospitalization ; Humans ; Infectious Disease ; Leishmaniasis, Visceral - diagnosis ; Leishmaniasis, Visceral - drug therapy ; Leishmaniasis, Visceral - epidemiology ; Male ; Mediterranean countries ; Retrospective Studies ; Romania - epidemiology ; Spain ; Time Factors ; Travel ; Travel history ; Travel medicine ; Treatment Outcome ; Vector-borne diseases</subject><ispartof>Travel medicine and infectious disease, 2009-01, Vol.7 (1), p.35-39</ispartof><rights>Elsevier Ltd</rights><rights>2008 Elsevier Ltd</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c440t-fc04a048c24ff1393c303facd025212006b0c3b8e79fdff4b74d9d385a018b1b3</citedby><cites>FETCH-LOGICAL-c440t-fc04a048c24ff1393c303facd025212006b0c3b8e79fdff4b74d9d385a018b1b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/1027116270?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,776,780,3536,27903,27904,64361,64363,64365,65309,72215</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19174299$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Neghina, Raul</creatorcontrib><creatorcontrib>Neghina, Adriana-Maria</creatorcontrib><creatorcontrib>Merkler, Carmen</creatorcontrib><creatorcontrib>Marincu, Iosif</creatorcontrib><creatorcontrib>Moldovan, Roxana</creatorcontrib><creatorcontrib>Iacobiciu, Ioan</creatorcontrib><title>Importation of visceral leishmaniasis in returning Romanian workers from Spain</title><title>Travel medicine and infectious disease</title><addtitle>Travel Med Infect Dis</addtitle><description>Summary Background Over the past two decades visceral leishmaniasis cases and foci have increased in Romania, where the disease has also become a medical concern. The following study aimed to provide essential knowledge on early diagnosis and management of visceral leishmaniasis cases in Romania acquired especially by traveling and working in the Mediterranean countries. Method Retrospective analysis of the medical records of the patients diagnosed with imported visceral leishmaniasis in a western Romanian county. Results Three patients with visceral leishmaniasis imported from Spain were admitted to hospital in Timisoara in 2005. Detailed case histories along with clinical and laboratory features are presented. In all the patients the final laboratory confirmation of the disease was by Giemsa-stained blood smears obtained by bone marrow biopsy. Conclusions Since 2004, many Romanian citizens left their homeland looking for a better job in the Mediterranean region. Unaware of the risks of outdoor labor in warm climatic conditions, they accepted to live and work in improper sanitary conditions. Late identification of the disease resulted mainly from failure of the physicians to diagnose and associate the syndrome with travel.</description><subject>Adult</subject><subject>Amphotericin B - therapeutic use</subject><subject>Antiprotozoal Agents - therapeutic use</subject><subject>Bone marrow</subject><subject>Bone marrow biopsy</subject><subject>Climatic conditions</subject><subject>Diagnosis, Differential</subject><subject>Fatal Outcome</subject><subject>Female</subject><subject>Giemsa-stained blood smears</subject><subject>Hospitalization</subject><subject>Humans</subject><subject>Infectious Disease</subject><subject>Leishmaniasis, Visceral - diagnosis</subject><subject>Leishmaniasis, Visceral - drug therapy</subject><subject>Leishmaniasis, Visceral - epidemiology</subject><subject>Male</subject><subject>Mediterranean countries</subject><subject>Retrospective Studies</subject><subject>Romania - epidemiology</subject><subject>Spain</subject><subject>Time Factors</subject><subject>Travel</subject><subject>Travel history</subject><subject>Travel medicine</subject><subject>Treatment Outcome</subject><subject>Vector-borne diseases</subject><issn>1477-8939</issn><issn>1873-0442</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFkV9rFTEQxYNYbK1-AkECgm97O_lzd5MHBSlVC0XB6nPIZiea293kmuyt9Ns323uh0BefMgy_M5lzhpA3DFYMWHu2Wc2TDcOKA6jaWQHwZ-SEqU40ICV_XmvZdY3SQh-Tl6VsAMRaSfGCHDPNOsm1PiHfLqdtyrOdQ4o0eXobisNsRzpiKH8mG4MtodAQacZ5l2OIv-mP9NCP9F_KN5gL9TlN9HprQ3xFjrwdC74-vKfk1-eLn-dfm6vvXy7PP101TkqYG-9AWpDKcek9E1o4AcJbNwBfc1YNtT040SvstB-8l30nBz0ItbbAVM96cUre7-duc_q7wzKbaVl8HG3EtCumbVXLNYcKvnsCblK1UXczDHjHWMu7hRJ7yuVUSkZvtjlMNt9VyCxhm415CNssYS_NGnZVvT3M3vUTDo-aQ7oV-LAHsEZxGzCb4gJGh0PI6GYzpPCfDz4-0bsxxODseIN3WB6dmMINmOvl3su5QQEwwbi4B5ROpeM</recordid><startdate>20090101</startdate><enddate>20090101</enddate><creator>Neghina, Raul</creator><creator>Neghina, Adriana-Maria</creator><creator>Merkler, Carmen</creator><creator>Marincu, Iosif</creator><creator>Moldovan, Roxana</creator><creator>Iacobiciu, Ioan</creator><general>Elsevier Ltd</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88C</scope><scope>88E</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>F1W</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H95</scope><scope>H97</scope><scope>K9.</scope><scope>KB0</scope><scope>L.G</scope><scope>M0S</scope><scope>M0T</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20090101</creationdate><title>Importation of visceral leishmaniasis in returning Romanian workers from Spain</title><author>Neghina, Raul ; Neghina, Adriana-Maria ; Merkler, Carmen ; Marincu, Iosif ; Moldovan, Roxana ; Iacobiciu, Ioan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c440t-fc04a048c24ff1393c303facd025212006b0c3b8e79fdff4b74d9d385a018b1b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Adult</topic><topic>Amphotericin B - therapeutic use</topic><topic>Antiprotozoal Agents - therapeutic use</topic><topic>Bone marrow</topic><topic>Bone marrow biopsy</topic><topic>Climatic conditions</topic><topic>Diagnosis, Differential</topic><topic>Fatal Outcome</topic><topic>Female</topic><topic>Giemsa-stained blood smears</topic><topic>Hospitalization</topic><topic>Humans</topic><topic>Infectious Disease</topic><topic>Leishmaniasis, Visceral - diagnosis</topic><topic>Leishmaniasis, Visceral - drug therapy</topic><topic>Leishmaniasis, Visceral - epidemiology</topic><topic>Male</topic><topic>Mediterranean countries</topic><topic>Retrospective Studies</topic><topic>Romania - epidemiology</topic><topic>Spain</topic><topic>Time Factors</topic><topic>Travel</topic><topic>Travel history</topic><topic>Travel medicine</topic><topic>Treatment Outcome</topic><topic>Vector-borne diseases</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Neghina, Raul</creatorcontrib><creatorcontrib>Neghina, Adriana-Maria</creatorcontrib><creatorcontrib>Merkler, Carmen</creatorcontrib><creatorcontrib>Marincu, Iosif</creatorcontrib><creatorcontrib>Moldovan, Roxana</creatorcontrib><creatorcontrib>Iacobiciu, Ioan</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Healthcare Administration Database (Alumni)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 1: Biological Sciences & Living Resources</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 3: Aquatic Pollution & Environmental Quality</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Travel medicine and infectious disease</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Neghina, Raul</au><au>Neghina, Adriana-Maria</au><au>Merkler, Carmen</au><au>Marincu, Iosif</au><au>Moldovan, Roxana</au><au>Iacobiciu, Ioan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Importation of visceral leishmaniasis in returning Romanian workers from Spain</atitle><jtitle>Travel medicine and infectious disease</jtitle><addtitle>Travel Med Infect Dis</addtitle><date>2009-01-01</date><risdate>2009</risdate><volume>7</volume><issue>1</issue><spage>35</spage><epage>39</epage><pages>35-39</pages><issn>1477-8939</issn><eissn>1873-0442</eissn><abstract>Summary Background Over the past two decades visceral leishmaniasis cases and foci have increased in Romania, where the disease has also become a medical concern. The following study aimed to provide essential knowledge on early diagnosis and management of visceral leishmaniasis cases in Romania acquired especially by traveling and working in the Mediterranean countries. Method Retrospective analysis of the medical records of the patients diagnosed with imported visceral leishmaniasis in a western Romanian county. Results Three patients with visceral leishmaniasis imported from Spain were admitted to hospital in Timisoara in 2005. Detailed case histories along with clinical and laboratory features are presented. In all the patients the final laboratory confirmation of the disease was by Giemsa-stained blood smears obtained by bone marrow biopsy. Conclusions Since 2004, many Romanian citizens left their homeland looking for a better job in the Mediterranean region. Unaware of the risks of outdoor labor in warm climatic conditions, they accepted to live and work in improper sanitary conditions. Late identification of the disease resulted mainly from failure of the physicians to diagnose and associate the syndrome with travel.</abstract><cop>Netherlands</cop><pub>Elsevier Ltd</pub><pmid>19174299</pmid><doi>10.1016/j.tmaid.2008.10.002</doi><tpages>5</tpages></addata></record> |
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subjects | Adult Amphotericin B - therapeutic use Antiprotozoal Agents - therapeutic use Bone marrow Bone marrow biopsy Climatic conditions Diagnosis, Differential Fatal Outcome Female Giemsa-stained blood smears Hospitalization Humans Infectious Disease Leishmaniasis, Visceral - diagnosis Leishmaniasis, Visceral - drug therapy Leishmaniasis, Visceral - epidemiology Male Mediterranean countries Retrospective Studies Romania - epidemiology Spain Time Factors Travel Travel history Travel medicine Treatment Outcome Vector-borne diseases |
title | Importation of visceral leishmaniasis in returning Romanian workers from Spain |
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