An overview of the relations between polymorphisms in drug metabolising enzymes and drug transporters and survival after cancer drug treatment

Summary A wide interindividual variability in survival after cancer treatment is observed. This is attributable to many factors, including tumour and patient related factors. Genetic polymorphisms in drug metabolising enzymes and drug transporters may be one of these factors. Drug metabolising enzym...

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Veröffentlicht in:Cancer treatment reviews 2009-02, Vol.35 (1), p.18-31
Hauptverfasser: Ekhart, Corine, Rodenhuis, Sjoerd, Smits, Paul H.M, Beijnen, Jos H, Huitema, Alwin D.R
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Sprache:eng
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