Osteopontin‐Deficiency Suppresses Growth of B16 Melanoma Cells Implanted in Bone and Osteoclastogenesis in Co‐Cultures

Tumor metastasis and invasion to bone is one of major medical issues in our modern societies. Osteopontin deficiency decreased tumor invasion in bone based on knockout mouse study. In bone, osteopontin is a positive factor to increase tumor invasion. Introduction: Osteopontin is an arginine‐glycine‐...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of bone and mineral research 2004-10, Vol.19 (10), p.1706-1711
Hauptverfasser:	Ohyama, Yoshio, Nemoto, Hiroyuki, Rittling, Susan, Tsuji, Kunikazu, Amagasa, Teruo, Denhardt, David T, Nifuji, Akira, Noda, Masaki
Format:	Artikel
Sprache:	eng
Schlagworte:	Acid Phosphatase - metabolism Animals Biological and medical sciences Bone Marrow - surgery bone marrow ablation Bone Marrow Cells - metabolism Bone Neoplasms - prevention & control Bone Neoplasms - secondary Bone Regeneration Cell Division Coculture Techniques Female Femur - surgery Fundamental and applied biological sciences. Psychology Isoenzymes - metabolism Male melanoma Melanoma, Experimental - prevention & control Melanoma, Experimental - secondary Mice Mice, Knockout Neoplasm Metastasis - physiopathology osteoclast Osteoclasts - metabolism Osteopontin Sialoglycoproteins - deficiency Sialoglycoproteins - physiology Skeleton and joints Tartrate-Resistant Acid Phosphatase Tumor Cells, Cultured tumor invasion Vertebrates: osteoarticular system, musculoskeletal system
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!