Detecting HIV Associated Neurocognitive Disorders in Adolescents: What Is the Best Screening Tool?
Abstract Purpose To examine the ability of the HIV-Dementia Scale (HDS) and Mini Mental State Exam (MMSE) to detect encephalopathy in adolescents living with human immunodeficiency virus (HIV) and/or acquired immunodeficency syndrome (AIDS). Method The study was based on chart review (N = 71) from 1...
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| Veröffentlicht in: | Journal of adolescent health 2009-02, Vol.44 (2), p.133-135 |
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| creator | Lyon, Maureen E., Ph.D McCarter, Robert, D.Sc D'Angelo, Lawrence J., M.D., M.P.H |
| description | Abstract Purpose To examine the ability of the HIV-Dementia Scale (HDS) and Mini Mental State Exam (MMSE) to detect encephalopathy in adolescents living with human immunodeficiency virus (HIV) and/or acquired immunodeficency syndrome (AIDS). Method The study was based on chart review (N = 71) from 1999 to 2006, extracting data from psychological testing, disease classification, and demographic variables. HDS and MMSE scores were independent. Diagnosis of encephalopathy used American Academy of Neurology Criteria. Receiver Operating Characteristic Curves were plotted. Results Six patients had encephalopathy. The HDS identified five of these cases (83% sensitivity, 76% specificity). The MMSE identified three cases (50% sensitivity, 92% specificity). Conclusion Based on the study results, the HDS appears to be clinically useful. |
| doi_str_mv | 10.1016/j.jadohealth.2008.06.023 |
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Method The study was based on chart review (N = 71) from 1999 to 2006, extracting data from psychological testing, disease classification, and demographic variables. HDS and MMSE scores were independent. Diagnosis of encephalopathy used American Academy of Neurology Criteria. Receiver Operating Characteristic Curves were plotted. Results Six patients had encephalopathy. The HDS identified five of these cases (83% sensitivity, 76% specificity). The MMSE identified three cases (50% sensitivity, 92% specificity). Conclusion Based on the study results, the HDS appears to be clinically useful.</description><identifier>ISSN: 1054-139X</identifier><identifier>EISSN: 1879-1972</identifier><identifier>DOI: 10.1016/j.jadohealth.2008.06.023</identifier><identifier>PMID: 19167661</identifier><identifier>CODEN: JAHCD9</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Acquired Immunodeficiency Syndrome - complications ; Adolescent ; Adolescent HIV ; Adolescents ; AIDS Dementia Complex - diagnosis ; Biological and medical sciences ; Encephalopathy ; Female ; HIV ; HIV Infections - complications ; HIV-associated neurocognitive disorders (HAND) ; HIV-Dementia Scale ; Human immunodeficiency virus ; Human viral diseases ; Humans ; Immunodeficiencies ; Immunodeficiencies. Immunoglobulinopathies ; Immunopathology ; Infectious diseases ; Male ; Medical sciences ; Mental Status Schedule ; Mini-Mental State Exam ; Minimental State Examination ; Neurocognitive functioning ; Pediatrics ; Psychiatric Status Rating Scales ; Psychology. Psychoanalysis. Psychiatry ; Psychometrics. Diagnostic aid systems ; Psychopathology. Psychiatry ; ROC Curve ; Self-Assessment ; Sensitivity ; Sensitivity and Specificity ; Surveys and Questionnaires ; Techniques and methods ; Viral diseases ; Viral diseases of the lymphoid tissue and the blood. Aids ; Young Adult</subject><ispartof>Journal of adolescent health, 2009-02, Vol.44 (2), p.133-135</ispartof><rights>Society for Adolescent Medicine</rights><rights>2009 Society for Adolescent Medicine</rights><rights>2009 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c519t-7d3f1adc35ff3c25dc31fd46731f18314b0793751bc6da84396dd6f89237fdcb3</citedby><cites>FETCH-LOGICAL-c519t-7d3f1adc35ff3c25dc31fd46731f18314b0793751bc6da84396dd6f89237fdcb3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jadohealth.2008.06.023$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,31000,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=21123893$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19167661$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lyon, Maureen E., Ph.D</creatorcontrib><creatorcontrib>McCarter, Robert, D.Sc</creatorcontrib><creatorcontrib>D'Angelo, Lawrence J., M.D., M.P.H</creatorcontrib><title>Detecting HIV Associated Neurocognitive Disorders in Adolescents: What Is the Best Screening Tool?</title><title>Journal of adolescent health</title><addtitle>J Adolesc Health</addtitle><description>Abstract Purpose To examine the ability of the HIV-Dementia Scale (HDS) and Mini Mental State Exam (MMSE) to detect encephalopathy in adolescents living with human immunodeficiency virus (HIV) and/or acquired immunodeficency syndrome (AIDS). Method The study was based on chart review (N = 71) from 1999 to 2006, extracting data from psychological testing, disease classification, and demographic variables. HDS and MMSE scores were independent. Diagnosis of encephalopathy used American Academy of Neurology Criteria. Receiver Operating Characteristic Curves were plotted. Results Six patients had encephalopathy. The HDS identified five of these cases (83% sensitivity, 76% specificity). The MMSE identified three cases (50% sensitivity, 92% specificity). Conclusion Based on the study results, the HDS appears to be clinically useful.</description><subject>Acquired Immunodeficiency Syndrome - complications</subject><subject>Adolescent</subject><subject>Adolescent HIV</subject><subject>Adolescents</subject><subject>AIDS Dementia Complex - diagnosis</subject><subject>Biological and medical sciences</subject><subject>Encephalopathy</subject><subject>Female</subject><subject>HIV</subject><subject>HIV Infections - complications</subject><subject>HIV-associated neurocognitive disorders (HAND)</subject><subject>HIV-Dementia Scale</subject><subject>Human immunodeficiency virus</subject><subject>Human viral diseases</subject><subject>Humans</subject><subject>Immunodeficiencies</subject><subject>Immunodeficiencies. Immunoglobulinopathies</subject><subject>Immunopathology</subject><subject>Infectious diseases</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Mental Status Schedule</subject><subject>Mini-Mental State Exam</subject><subject>Minimental State Examination</subject><subject>Neurocognitive functioning</subject><subject>Pediatrics</subject><subject>Psychiatric Status Rating Scales</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychometrics. Diagnostic aid systems</subject><subject>Psychopathology. Psychiatry</subject><subject>ROC Curve</subject><subject>Self-Assessment</subject><subject>Sensitivity</subject><subject>Sensitivity and Specificity</subject><subject>Surveys and Questionnaires</subject><subject>Techniques and methods</subject><subject>Viral diseases</subject><subject>Viral diseases of the lymphoid tissue and the blood. Aids</subject><subject>Young Adult</subject><issn>1054-139X</issn><issn>1879-1972</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>7QJ</sourceid><recordid>eNqNkktv1TAQhSMEoqXwF5A3sEvqR-IHC9BtS-mVKli0PHaWY096HXLj1k4q9d_j6F5RiU2RFzOLb84c-UxRIIIrggk_7qveuLABM0ybimIsK8wrTNmz4pBIoUqiBH2ee9zUJWHq10HxKqUe51FO8MvigCjCRe4Pi_YMJrCTH2_QxfoHWqUUrDcTOPQV5hhsuBn95O8BnfkUooOYkB_RyoUBkoVxSh_Qz42Z0DqhaQPoBNKErmwEGBfJ6xCGT6-LF50ZErzZ16Pi-_nn69OL8vLbl_Xp6rK0DVFTKRzriHGWNV3HLG1yRzpXc5ELkYzULRaKiYa0ljsja6a4c7yTijLROduyo-L9Tvc2hrs5G9Fbnz0OgxkhzElzLhue35NgI2gtBVZPghQzJaQiGZQ70MaQUoRO30a_NfFBE6yXxHSvHxPTS2Iac50Ty6Nv9zvmdgvucXAfUQbe7QGTrBm6aEbr01-OEkKZVIvQyY6D_Mf3HqJO1sNowfmYE9Yu-P9x8_EfETv40ee9v-EBUh_mOOYMNdGJaqyvlgtbDgxLjBmmiv0BeqDN8g</recordid><startdate>20090201</startdate><enddate>20090201</enddate><creator>Lyon, Maureen E., Ph.D</creator><creator>McCarter, Robert, D.Sc</creator><creator>D'Angelo, Lawrence J., M.D., M.P.H</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7U9</scope><scope>H94</scope><scope>7QJ</scope><scope>7X8</scope></search><sort><creationdate>20090201</creationdate><title>Detecting HIV Associated Neurocognitive Disorders in Adolescents: What Is the Best Screening Tool?</title><author>Lyon, Maureen E., Ph.D ; McCarter, Robert, D.Sc ; D'Angelo, Lawrence J., M.D., M.P.H</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c519t-7d3f1adc35ff3c25dc31fd46731f18314b0793751bc6da84396dd6f89237fdcb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Acquired Immunodeficiency Syndrome - complications</topic><topic>Adolescent</topic><topic>Adolescent HIV</topic><topic>Adolescents</topic><topic>AIDS Dementia Complex - diagnosis</topic><topic>Biological and medical sciences</topic><topic>Encephalopathy</topic><topic>Female</topic><topic>HIV</topic><topic>HIV Infections - complications</topic><topic>HIV-associated neurocognitive disorders (HAND)</topic><topic>HIV-Dementia Scale</topic><topic>Human immunodeficiency virus</topic><topic>Human viral diseases</topic><topic>Humans</topic><topic>Immunodeficiencies</topic><topic>Immunodeficiencies. Immunoglobulinopathies</topic><topic>Immunopathology</topic><topic>Infectious diseases</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Mental Status Schedule</topic><topic>Mini-Mental State Exam</topic><topic>Minimental State Examination</topic><topic>Neurocognitive functioning</topic><topic>Pediatrics</topic><topic>Psychiatric Status Rating Scales</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychometrics. Diagnostic aid systems</topic><topic>Psychopathology. Psychiatry</topic><topic>ROC Curve</topic><topic>Self-Assessment</topic><topic>Sensitivity</topic><topic>Sensitivity and Specificity</topic><topic>Surveys and Questionnaires</topic><topic>Techniques and methods</topic><topic>Viral diseases</topic><topic>Viral diseases of the lymphoid tissue and the blood. Aids</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lyon, Maureen E., Ph.D</creatorcontrib><creatorcontrib>McCarter, Robert, D.Sc</creatorcontrib><creatorcontrib>D'Angelo, Lawrence J., M.D., M.P.H</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Applied Social Sciences Index & Abstracts (ASSIA)</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of adolescent health</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lyon, Maureen E., Ph.D</au><au>McCarter, Robert, D.Sc</au><au>D'Angelo, Lawrence J., M.D., M.P.H</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Detecting HIV Associated Neurocognitive Disorders in Adolescents: What Is the Best Screening Tool?</atitle><jtitle>Journal of adolescent health</jtitle><addtitle>J Adolesc Health</addtitle><date>2009-02-01</date><risdate>2009</risdate><volume>44</volume><issue>2</issue><spage>133</spage><epage>135</epage><pages>133-135</pages><issn>1054-139X</issn><eissn>1879-1972</eissn><coden>JAHCD9</coden><abstract>Abstract Purpose To examine the ability of the HIV-Dementia Scale (HDS) and Mini Mental State Exam (MMSE) to detect encephalopathy in adolescents living with human immunodeficiency virus (HIV) and/or acquired immunodeficency syndrome (AIDS). Method The study was based on chart review (N = 71) from 1999 to 2006, extracting data from psychological testing, disease classification, and demographic variables. HDS and MMSE scores were independent. Diagnosis of encephalopathy used American Academy of Neurology Criteria. Receiver Operating Characteristic Curves were plotted. Results Six patients had encephalopathy. The HDS identified five of these cases (83% sensitivity, 76% specificity). The MMSE identified three cases (50% sensitivity, 92% specificity). Conclusion Based on the study results, the HDS appears to be clinically useful.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>19167661</pmid><doi>10.1016/j.jadohealth.2008.06.023</doi><tpages>3</tpages></addata></record> |
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| ispartof | Journal of adolescent health, 2009-02, Vol.44 (2), p.133-135 |
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| subjects | Acquired Immunodeficiency Syndrome - complications Adolescent Adolescent HIV Adolescents AIDS Dementia Complex - diagnosis Biological and medical sciences Encephalopathy Female HIV HIV Infections - complications HIV-associated neurocognitive disorders (HAND) HIV-Dementia Scale Human immunodeficiency virus Human viral diseases Humans Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Infectious diseases Male Medical sciences Mental Status Schedule Mini-Mental State Exam Minimental State Examination Neurocognitive functioning Pediatrics Psychiatric Status Rating Scales Psychology. Psychoanalysis. Psychiatry Psychometrics. Diagnostic aid systems Psychopathology. Psychiatry ROC Curve Self-Assessment Sensitivity Sensitivity and Specificity Surveys and Questionnaires Techniques and methods Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Young Adult |
| title | Detecting HIV Associated Neurocognitive Disorders in Adolescents: What Is the Best Screening Tool? |
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