Non-erythroid activities of erythropoietin: Functional effects on murine dendritic cells

Erythropoietin (EPO) is the main hormone that promotes proliferation and differentiation of erythroid progenitor cells via binding to its surface receptor (EPO-R). Recent studies suggest that this hormone may affect also other cell types, besides the red blood cell lineage. We have previously demons...

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Veröffentlicht in:	Molecular immunology 2009-02, Vol.46 (4), p.713-721
Hauptverfasser:	Lifshitz, Lilach, Prutchi-Sagiv, Sara, Avneon, Maayan, Gassmann, Max, Mittelman, Moshe, Neumann, Drorit
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals B7-1 Antigen - immunology B7-1 Antigen - metabolism B7-2 Antigen - immunology B7-2 Antigen - metabolism Bone Marrow Cells - immunology Bone Marrow Cells - metabolism Co-stimulatory molecules Cytokines - immunology Cytokines - metabolism Dendritic Cells - immunology Dendritic Cells - metabolism EPO-R Erythropoietin - immunology Erythropoietin - metabolism Female Humans Mice Mice, Inbred C57BL Mice, Transgenic Phosphorylation - immunology Receptors, Erythropoietin - immunology Receptors, Erythropoietin - metabolism Signal transduction Signal Transduction - immunology Spleen - immunology Spleen - metabolism STAT STAT3 Transcription Factor - immunology STAT3 Transcription Factor - metabolism STAT5 Transcription Factor - immunology STAT5 Transcription Factor - metabolism
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