Enhancing antiretroviral therapy for human immunodeficiency virus cognitive disorders

The benefits of combination antiretroviral therapy (ART) for HIV cognitive disorders vary substantially between individuals. This study evaluated whether cerebrospinal fluid (CSF) drug penetration and CSF virological suppression influence the extent of neuropsychological (NP) improvement during ART....

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Veröffentlicht in:	Annals of neurology 2004-09, Vol.56 (3), p.416-423
Hauptverfasser:	Letendre, Scott L., McCutchan, J. Allen, Childers, Meredith E., Woods, Steven P., Lazzaretto, Deborah, Heaton, Robert K., Grant, Igor, Ellis, Ronald J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anti-Retroviral Agents - pharmacology Anti-Retroviral Agents - therapeutic use Biological and medical sciences Chi-Square Distribution Cognition Disorders - cerebrospinal fluid Cognition Disorders - drug therapy Cognition Disorders - psychology Female HIV Infections - drug therapy HIV Infections - psychology HIV-1 - drug effects HIV-1 - metabolism Human immunodeficiency virus Humans Male Medical sciences Middle Aged Multivariate Analysis Neurology Neuropsychological Tests - statistics & numerical data Prospective Studies Statistics, Nonparametric
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