Hereditary breast cancer syndromes and clinical implications

Summary Breast cancer is the most common cancer in the UK, and a significant number of breast cancers are hereditary. Identification of BRCA1/2 genes and the high-risk patients for developing breast cancer would allow a better understanding of the natural history and pathogenesis of breast cancer. G...

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Veröffentlicht in:	Journal of plastic, reconstructive & aesthetic surgery reconstructive & aesthetic surgery, 2009-02, Vol.62 (2), p.181-189
Hauptverfasser:	Majdak-Paredes, E.J, Fatah, F
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences BRCA1 BRCA2 Breast Neoplasms - genetics Breast Neoplasms - prevention & control Breast reconstruction Checkpoint Kinase 2 Female Genes, BRCA1 Genes, BRCA2 Genetic Predisposition to Disease Genetic Testing - methods Gynecology. Andrology. Obstetrics Healthy mutation carriers Hereditary breast cancer Humans Mammaplasty - methods Mammary gland diseases Mastectomy - methods Medical sciences Mutation Neoplastic Syndromes, Hereditary - genetics Neoplastic Syndromes, Hereditary - prevention & control Plastic Surgery Protein-Serine-Threonine Kinases - genetics Radiotherapy, Adjuvant Risk-reducing mastectomy Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the genital tract and mammary gland Tumors
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