Anticancer effects of (−)-epigallocatechin-3-gallate on ovarian carcinoma cell lines

Purpose: A constituent of green tea, (−)-epigallocatechin-3-gallate (EGCG), has been known to possess anti-cancer properties. In this study, we investigated the time-course anticancer effects of EGCG on human ovarian cancer cells to provide insights into the molecular-level understanding of growth s...

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Veröffentlicht in:	Gynecologic oncology 2004-09, Vol.94 (3), p.760-768
Hauptverfasser:	Huh, Seung Won, Bae, Su Mi, Kim, Yong-Wan, Lee, Joon Mo, Namkoong, Sung Eun, Lee, Insu P., Kim, Sang Hee, Kim, Chong Kook, Ahn, Woong Shick
Format:	Artikel
Sprache:	eng
Schlagworte:	(−)-epigallocatechin-3-gallate (EGCG) Antineoplastic Agents, Phytogenic - pharmacokinetics Antineoplastic Agents, Phytogenic - pharmacology Apoptosis Apoptosis - drug effects Catechin - analogs & derivatives Catechin - pharmacokinetics Catechin - pharmacology Cdc20 Proteins Cell Cycle Cell Cycle - drug effects Cell Cycle Proteins - biosynthesis Cell Cycle Proteins - genetics Cell Division - drug effects Cell Line, Tumor Cyclin A - biosynthesis Cyclin A - genetics Cyclin B - biosynthesis Cyclin B - genetics Cyclin B1 Dose-Response Relationship, Drug Female Humans Ovarian Cancer Ovarian Neoplasms - drug therapy Ovarian Neoplasms - metabolism Ovarian Neoplasms - pathology RNA, Messenger - biosynthesis RNA, Messenger - genetics
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