Selective priming to Toll‐like receptor 4 (TLR4), not TLR2, ligands by P. acnes involves up‐regulation of MD‐2 in mice

Lipopolysaccharide (LPS) triggers cytokine production through Toll‐like receptor 4 (TLR4), which shares downstream signaling pathways with TLR2. We investigated the roles of TLR2 and TLR4 in Propionibacterium acnes (P. acnes)–primed, LPS‐induced liver damage using selective TLR ligands. Stock LPS in...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Hepatology (Baltimore, Md.) Md.), 2004-09, Vol.40 (3), p.555-564
Hauptverfasser:	Romics, Laszlo, Dolganiuc, Angela, Kodys, Karen, Drechsler, Yvonne, Oak, Shilpa, Velayudham, Arumugam, Mandrekar, Pranoti, Szabo, Gyongyi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal cells Animals Antigens, Ly - biosynthesis Biological and medical sciences Cell cultures. Hybridization. Fusion Cytokines - biosynthesis Female Fundamental and applied biological sciences. Psychology Interferon-gamma - physiology Lipopolysaccharide Receptors - biosynthesis Lipopolysaccharides - pharmacology Liver - metabolism Lymphocyte Antigen 96 Membrane Glycoproteins - physiology Mice Mice, Inbred C57BL Molecular and cellular biology Propionibacterium acnes - immunology Receptors, Cell Surface - physiology Toll-Like Receptor 1 Toll-Like Receptor 2 Toll-Like Receptor 4 Toll-Like Receptors Up-Regulation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!