Combined spectral karyotyping, multicolor banding, and microarray comparative genomic hybridization analysis provides a detailed characterization of complex structural chromosomal rearrangements associated with gene amplification in the osteosarcoma cell line MG-63

The advancement of fluorescence in situ hybridization–based assays has permitted more refined delineation of chromosomal loci involved in complex chromosomal rearrangements (CCRs) and gene amplification. In this detailed molecular cytogenetic analysis, spectral karyotyping (SKY), multicolor banding...

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Veröffentlicht in:	Cancer genetics and cytogenetics 2004-09, Vol.153 (2), p.158-164
Hauptverfasser:	Lim, Gloria, Karaskova, Jana, Vukovic, Bisera, Bayani, Jane, Beheshti, Ben, Bernardini, Marcus, Squire, Jeremy A., Zielenska, Maria
Format:	Artikel
Sprache:	eng
Schlagworte:	Bone Neoplasms - genetics Cell Line, Tumor Chromosome Banding Chromosome Mapping Gene Amplification - genetics Gene Rearrangement - genetics Humans Karyotyping Nucleic Acid Hybridization - methods Oligonucleotide Array Sequence Analysis - methods Osteosarcoma - genetics
Online-Zugang:	Volltext
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