Micro and nano-fabrication of biodegradable polymers for drug delivery
This paper presents state-of-the-art micro and nano-fabrication techniques for biodegradable polymers. Replication molding, using a rigid or elastic master, can pattern structures on a polymer surface in a submicron resolution at a low cost. Layer-by-layer rapid prototyping methods are promising in...
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Veröffentlicht in: | Advanced drug delivery reviews 2004-09, Vol.56 (11), p.1621-1633 |
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description | This paper presents state-of-the-art micro and nano-fabrication techniques for biodegradable polymers. Replication molding, using a rigid or elastic master, can pattern structures on a polymer surface in a submicron resolution at a low cost. Layer-by-layer rapid prototyping methods are promising in producing controlled release units with complicated geometries, release mechanisms and the ability to control microstructure and composition. Special attention is paid to the fast, flexible, and non-invasive laser fabrication techniques that have great potential in the fabrication of biodegradable polymer drug delivery devices in both a laboratory and industry scale. |
doi_str_mv | 10.1016/j.addr.2004.05.002 |
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Replication molding, using a rigid or elastic master, can pattern structures on a polymer surface in a submicron resolution at a low cost. Layer-by-layer rapid prototyping methods are promising in producing controlled release units with complicated geometries, release mechanisms and the ability to control microstructure and composition. Special attention is paid to the fast, flexible, and non-invasive laser fabrication techniques that have great potential in the fabrication of biodegradable polymer drug delivery devices in both a laboratory and industry scale.</description><identifier>ISSN: 0169-409X</identifier><identifier>EISSN: 1872-8294</identifier><identifier>DOI: 10.1016/j.addr.2004.05.002</identifier><identifier>PMID: 15350292</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Absorbable Implants ; Biodegradable polymer ; Capsules ; Drug delivery ; Drug Delivery Systems - methods ; Microfabrication ; Nanofabrication ; Nanotechnology - methods ; Polymers - administration & dosage ; Polymers - chemical synthesis</subject><ispartof>Advanced drug delivery reviews, 2004-09, Vol.56 (11), p.1621-1633</ispartof><rights>2004 Elsevier B.V.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c480t-88df5e40abe337c068e6b77a143d5011145445192a2b528eb49f1e24612f5fa53</citedby><cites>FETCH-LOGICAL-c480t-88df5e40abe337c068e6b77a143d5011145445192a2b528eb49f1e24612f5fa53</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.addr.2004.05.002$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,778,782,3539,27911,27912,45982</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15350292$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lu, Y.</creatorcontrib><creatorcontrib>Chen, S.C.</creatorcontrib><title>Micro and nano-fabrication of biodegradable polymers for drug delivery</title><title>Advanced drug delivery reviews</title><addtitle>Adv Drug Deliv Rev</addtitle><description>This paper presents state-of-the-art micro and nano-fabrication techniques for biodegradable polymers. Replication molding, using a rigid or elastic master, can pattern structures on a polymer surface in a submicron resolution at a low cost. Layer-by-layer rapid prototyping methods are promising in producing controlled release units with complicated geometries, release mechanisms and the ability to control microstructure and composition. Special attention is paid to the fast, flexible, and non-invasive laser fabrication techniques that have great potential in the fabrication of biodegradable polymer drug delivery devices in both a laboratory and industry scale.</description><subject>Absorbable Implants</subject><subject>Biodegradable polymer</subject><subject>Capsules</subject><subject>Drug delivery</subject><subject>Drug Delivery Systems - methods</subject><subject>Microfabrication</subject><subject>Nanofabrication</subject><subject>Nanotechnology - methods</subject><subject>Polymers - administration & dosage</subject><subject>Polymers - chemical synthesis</subject><issn>0169-409X</issn><issn>1872-8294</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkT1PwzAURS0EglL4AwwoE1vCe46dxBILQnxJIBaQ2Cwnfq5cpXGxW6T-e1K1EhtMdzn3DvcwdoFQIGB1PS-MtbHgAKIAWQDwAzbBpuZ5w5U4ZJMRUrkA9XnCTlOaAyCvKzhmJyhLCVzxCXt49V0MmRlsNpgh5M600Xdm5cOQBZe1PliaRWNN21O2DP1mQTFlLsTMxvUss9T7b4qbM3bkTJ_ofJ9T9vFw_373lL-8PT7f3b7knWhglTeNdZIEmJbKsu6gaqhq69qgKK0ERBRSCImKG95K3lArlEPiokLupDOynLKr3e4yhq81pZVe-NRR35uBwjrpqmpEDQr_BcsSQPGS_wtizVWNQowg34HjXylFcnoZ_cLEjUbQWx96rrc-9NaHBqlHH2Ppcr--bhdkfyt7ASNwswNofO3bU9Sp8zR0ZH2kbqVt8H_t_wD_QZpc</recordid><startdate>20040922</startdate><enddate>20040922</enddate><creator>Lu, Y.</creator><creator>Chen, S.C.</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>7U5</scope><scope>L7M</scope><scope>7X8</scope></search><sort><creationdate>20040922</creationdate><title>Micro and nano-fabrication of biodegradable polymers for drug delivery</title><author>Lu, Y. ; Chen, S.C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c480t-88df5e40abe337c068e6b77a143d5011145445192a2b528eb49f1e24612f5fa53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Absorbable Implants</topic><topic>Biodegradable polymer</topic><topic>Capsules</topic><topic>Drug delivery</topic><topic>Drug Delivery Systems - methods</topic><topic>Microfabrication</topic><topic>Nanofabrication</topic><topic>Nanotechnology - methods</topic><topic>Polymers - administration & dosage</topic><topic>Polymers - chemical synthesis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lu, Y.</creatorcontrib><creatorcontrib>Chen, S.C.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>MEDLINE - Academic</collection><jtitle>Advanced drug delivery reviews</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lu, Y.</au><au>Chen, S.C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Micro and nano-fabrication of biodegradable polymers for drug delivery</atitle><jtitle>Advanced drug delivery reviews</jtitle><addtitle>Adv Drug Deliv Rev</addtitle><date>2004-09-22</date><risdate>2004</risdate><volume>56</volume><issue>11</issue><spage>1621</spage><epage>1633</epage><pages>1621-1633</pages><issn>0169-409X</issn><eissn>1872-8294</eissn><abstract>This paper presents state-of-the-art micro and nano-fabrication techniques for biodegradable polymers. 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subjects | Absorbable Implants Biodegradable polymer Capsules Drug delivery Drug Delivery Systems - methods Microfabrication Nanofabrication Nanotechnology - methods Polymers - administration & dosage Polymers - chemical synthesis |
title | Micro and nano-fabrication of biodegradable polymers for drug delivery |
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