Overexpression of heme oxygenase-1 in coronary atherosclerosis of Japanese autopsies with diabetes mellitus: Hisayama study

Abstract Few studies regarding the topographical expression of heme oxygenase-1 (HO-1) and its pathophysiological role in human coronary atherosclerotic lesions, particularly in relation to type 2 diabetes mellitus (DM) and intimal angiogenesis, have been reported. HO-1 expression was immunohistoche...

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Veröffentlicht in:	Atherosclerosis 2009-02, Vol.202 (2), p.573-581
Hauptverfasser:	Song, Jingyu, Sumiyoshi, Shinji, Nakashima, Yutaka, Doi, Yasufumi, Iida, Mitsuo, Kiyohara, Yutaka, Sueishi, Katsuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Asian Continental Ancestry Group - genetics Asian Continental Ancestry Group - statistics & numerical data Associated diseases and complications Atherosclerosis Atherosclerosis (general aspects, experimental research) Autopsy Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Cardiovascular Coronary Artery Disease - ethnology Coronary Artery Disease - metabolism Coronary Artery Disease - pathology Coronary Vessels - enzymology Coronary Vessels - pathology Diabetes mellitus Diabetes Mellitus, Type 2 - ethnology Diabetes Mellitus, Type 2 - metabolism Diabetes Mellitus, Type 2 - pathology Diabetes. Impaired glucose tolerance Diabetic Angiopathies - ethnology Diabetic Angiopathies - pathology Diabetic Angiopathies - physiopathology Endocrine pancreas. Apud cells (diseases) Endocrinopathies Female Heme oxygenase-1 Heme Oxygenase-1 - metabolism Human coronary artery Humans Immunohistochemistry Macrophages - pathology Male Medical sciences Middle Aged Myocytes, Smooth Muscle - pathology Neovascularization, Physiologic Risk Factors
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