Bone density, strength, and formation in adult cathepsin K (−/−) mice

Abstract Cathepsin K (CatK) is a cysteine protease expressed predominantly in osteoclasts, that plays a prominent role in degrading Type I collagen. Growing CatK null mice have osteopetrosis associated with a reduced ability to degrade bone matrix. Bone strength and histomorphometric endpoints in yo...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Bone (New York, N.Y.) N.Y.), 2009-02, Vol.44 (2), p.199-207
Hauptverfasser:	Pennypacker, B, Shea, M, Liu, Q, Masarachia, P, Saftig, P, Rodan, S, Rodan, G, Kimmel, D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Biomechanical Phenomena Bone and Bones - anatomy & histology Bone and Bones - enzymology Bone and Bones - physiology Bone Density - physiology Bone quality Bone Resorption - enzymology Cathepsin K Cathepsins - deficiency Cathepsins - metabolism Density Female Femur - anatomy & histology Femur - enzymology Formation Fundamental and applied biological sciences. Psychology Histomorphometry Investigative techniques, diagnostic techniques (general aspects) Lumbar Vertebrae - enzymology Lumbar Vertebrae - physiology Male Medical sciences Mice Microscopy, Fluorescence Organ Size Orthopedics Osteoarticular system. Muscles Osteogenesis Radiodiagnosis. Nmr imagery. Nmr spectrometry Regression Analysis Sex Characteristics Strength Surface Properties Vertebrates: anatomy and physiology, studies on body, several organs or systems
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!