DNA binding, cytotoxicity, apoptotic inducing activity, and molecular modeling study of quercetin zinc(II) complex

DNA cleavage activity of quercetin zinc(II) complex has been studied, but little attention has been devoted to the relationship between antitumor activity of this complex and DNA-binding properties. DNA-binding properties of quercetin zinc(II) complex were studied using UV–vis spectra, fluorescence...

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Veröffentlicht in:	Bioorganic & medicinal chemistry 2009-01, Vol.17 (2), p.614-620
Hauptverfasser:	Tan, Jun, Wang, Bochu, Zhu, Liancai
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic agents Antitumor activity Apoptosis Biological and medical sciences Cell Line, Tumor DNA - metabolism DNA binding General aspects Humans Intercalating Agents Intercalation Medical sciences Models, Molecular Pharmacology. Drug treatments Quercetin - chemistry Quercetin zinc(II) complex Zinc - chemistry
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