Regions of High Antigenicity within the Hypothetical PPE Major Polymorphic Tandem Repeat Open- Reading Frame, Rv2608, Show a Differential Humoral Response and a Low T Cell Response in Various Categories of Patients with Tuberculosis

The function of the PE/PPE families of proteins, which represent ∼10% of the coding capacity of the Mycobacterium tuberculosis genome, has remained relatively unknown. We earlier described a PPE family member, Rv2430c, as an immunodominant antigen. We now report another PPE family gene, Rv2608, a me...

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