Differences in Survival, Brain Damage, and Cerebrospinal Fluid Cytokine Kinetics Due to Meningitis Caused by 3 Different Streptococcus pneumoniae Serotypes: Evaluation in Humans and in 2 Experimental Models

Background. Experimental meningitis with Streptococcus pneumoniae serotypes 1, 3, and 9 has resulted in pronounced differences in disease severity, but clinical meningitis studies addressing serotype-related differences in case-fatality rates are lacking. Methods. Study subjects were Danish patients...

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