Breast Radiotherapy after Lumpectomy — No Longer Always Necessary
Breast-conserving surgery followed by radiotherapy is the standard of care for women with small breast cancers who wish to avoid mastectomy. This approach achieves good local control, does not disturb the women's body image or impair survival, 1 and has been an important step forward in the man...
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| Veröffentlicht in: | The New England journal of medicine 2004-09, Vol.351 (10), p.1021-1023 |
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| container_title | The New England journal of medicine |
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| creator | Smith, Ian E Ross, Gillian M |
| description | Breast-conserving surgery followed by radiotherapy is the standard of care for women with small breast cancers who wish to avoid mastectomy. This approach achieves good local control, does not disturb the women's body image or impair survival,
1
and has been an important step forward in the management of this disease.
Several trials have compared breast-conserving surgery plus postoperative radiotherapy with breast-conserving surgery alone, and all have shown an increased risk of local recurrence if radiotherapy is omitted but no difference in survival. One of the largest of these trials, the National Surgical Adjuvant Breast and Bowel Project (NSABP) B-06 study, . . . |
| doi_str_mv | 10.1056/NEJMe048173 |
| format | Article |
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1
and has been an important step forward in the management of this disease.
Several trials have compared breast-conserving surgery plus postoperative radiotherapy with breast-conserving surgery alone, and all have shown an increased risk of local recurrence if radiotherapy is omitted but no difference in survival. One of the largest of these trials, the National Surgical Adjuvant Breast and Bowel Project (NSABP) B-06 study, . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJMe048173</identifier><identifier>PMID: 15342811</identifier><identifier>CODEN: NEJMAG</identifier><language>eng</language><publisher>United States: Massachusetts Medical Society</publisher><subject>Age Factors ; Aged ; Antineoplastic Agents, Hormonal - therapeutic use ; Breast cancer ; Breast Neoplasms - radiotherapy ; Breast Neoplasms - therapy ; Combined Modality Therapy ; Female ; Humans ; Mastectomy ; Mastectomy, Segmental ; Middle Aged ; Neoplasm Recurrence, Local ; Neoplasms, Hormone-Dependent - therapy ; Tamoxifen - therapeutic use ; Therapy ; Tumors</subject><ispartof>The New England journal of medicine, 2004-09, Vol.351 (10), p.1021-1023</ispartof><rights>Copyright © 2004 Massachusetts Medical Society. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c379t-81899f39b440d32e61832a8838ce61d9fab735c3674630bbc2616c8a615b2ee83</citedby><cites>FETCH-LOGICAL-c379t-81899f39b440d32e61832a8838ce61d9fab735c3674630bbc2616c8a615b2ee83</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJMe048173$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/223933475?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>315,781,785,2760,2761,26108,27929,27930,52387,54069,64390,64392,64394,72474</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15342811$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Smith, Ian E</creatorcontrib><creatorcontrib>Ross, Gillian M</creatorcontrib><title>Breast Radiotherapy after Lumpectomy — No Longer Always Necessary</title><title>The New England journal of medicine</title><addtitle>N Engl J Med</addtitle><description>Breast-conserving surgery followed by radiotherapy is the standard of care for women with small breast cancers who wish to avoid mastectomy. This approach achieves good local control, does not disturb the women's body image or impair survival,
1
and has been an important step forward in the management of this disease.
Several trials have compared breast-conserving surgery plus postoperative radiotherapy with breast-conserving surgery alone, and all have shown an increased risk of local recurrence if radiotherapy is omitted but no difference in survival. 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This approach achieves good local control, does not disturb the women's body image or impair survival,
1
and has been an important step forward in the management of this disease.
Several trials have compared breast-conserving surgery plus postoperative radiotherapy with breast-conserving surgery alone, and all have shown an increased risk of local recurrence if radiotherapy is omitted but no difference in survival. One of the largest of these trials, the National Surgical Adjuvant Breast and Bowel Project (NSABP) B-06 study, . . .</abstract><cop>United States</cop><pub>Massachusetts Medical Society</pub><pmid>15342811</pmid><doi>10.1056/NEJMe048173</doi><tpages>3</tpages></addata></record> |
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| subjects | Age Factors Aged Antineoplastic Agents, Hormonal - therapeutic use Breast cancer Breast Neoplasms - radiotherapy Breast Neoplasms - therapy Combined Modality Therapy Female Humans Mastectomy Mastectomy, Segmental Middle Aged Neoplasm Recurrence, Local Neoplasms, Hormone-Dependent - therapy Tamoxifen - therapeutic use Therapy Tumors |
| title | Breast Radiotherapy after Lumpectomy — No Longer Always Necessary |
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