Bone marrow histology in marginal zone B-cell lymphomas: correlation with clinical parameters and flow cytometry in 120 patients
Background: Among marginal zone lymphomas (MZLs), bone marrow (BM) involvement features are well established in the splenic marginal zone lymphoma (SMZL); few data are available for extranodal marginal zone lymphoma (EMZL) and nodal marginal zone lymphoma (NMZL). Patients and methods: Incidence and...
Gespeichert in:
| Veröffentlicht in: | Annals of oncology 2009-01, Vol.20 (1), p.129-136 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 136 |
|---|---|
| container_issue | 1 |
| container_start_page | 129 |
| container_title | Annals of oncology |
| container_volume | 20 |
| creator | Boveri, E. Arcaini, L. Merli, M. Passamonti, F. Rizzi, S. Vanelli, L. Rumi, E. Rattotti, S. Lucioni, M. Picone, C. Castello, A. Pascutto, C. Magrini, U. Lazzarino, M. Paulli, M. |
| description | Background: Among marginal zone lymphomas (MZLs), bone marrow (BM) involvement features are well established in the splenic marginal zone lymphoma (SMZL); few data are available for extranodal marginal zone lymphoma (EMZL) and nodal marginal zone lymphoma (NMZL).
Patients and methods: Incidence and patterns of histologic BM involvement are studied in 120 MZL patients (48 SMZL, 59 EMZL, 13 NMZL) at onset and during follow-up; relationships between clinical features, BM histology and flow cytometry (FC) are analyzed.
Results: At diagnosis, BM involvement occurs in 90% SMZL, 22% EMZL and 54% NMZL (P < 0.0001); at reevaluation, incidence raises to 96% in SMZL and 34% in EMZL. Concordance between histology and FC is found in 87% of cases; most discordant cases have positive histology but negative FC. SMZL and EMZL show a nodular BM infiltration; the interstitial pattern is frequent in NMZL (P < 0.0001); sinusoidal localization is typical of SMZL, frequent in NMZL and occasional in EMZL (P = 0.0001). Stage, leukemic disease, B symptoms, more than one extranodal involved site, splenomegaly, elevated β2-microglobulin, serum monoclonal component, International Prognostic Index (IPI) and age-adjusted IPI are directly related to BM infiltration.
Conclusions: The different prevalence of BM involvement in MZL subtypes reflects their heterogeneous dissemination modalities; histology seems more sensible than FC to detect BM infiltration; development of BM involvement during follow-up is typical of EMZL. |
| doi_str_mv | 10.1093/annonc/mdn563 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_66830732</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><oup_id>10.1093/annonc/mdn563</oup_id><els_id>S0923753419399715</els_id><sourcerecordid>1631051241</sourcerecordid><originalsourceid>FETCH-LOGICAL-c506t-e46bcb405fa22b40624f1bd5466de9400793eae14ce068258b41ccc50d8a542f3</originalsourceid><addsrcrecordid>eNqF0c-L1DAUB_Agiju7evQqRVC81E2aH228ueOPFQY8qCB7CZn0dSdrm9QkdXc8-aebsWUFQczlQfjkJXlfhB4R_IJgSU-1c96Z06F1XNA7aEW4kGWDGbmLVlhWtKw5ZUfoOMYrjLGQlbyPjkhTkyavFfp55h0Ugw7BXxc7G5Pv_eW-sO6wd2md7osfB3FWGuj7ot8P484POr4sjA8Bep2sd8W1TbvC9NZZkw-MOugBEoRYaNcWXZ9bm33yeS_8bk0qnFGy4FJ8gO51uo_wcKkn6PPbN5_W5-Xmw7v361eb0nAsUglMbM2WYd7pqspVVKwj25YzIVqQDONaUtBAmAEsmoo3W0aMyWfbRnNWdfQEPZv7jsF_myAmNdh4-JN24KeohGgormmV4ZO_4JWfQh5EVEQKQUkjeUbljEzwMQbo1BhsntheEawOuag5FzXnkv3jpem0HaD9o5cgMni6AB3zDLugnbHx1lV5ZExSnN3z2flp_O-dyxtzqnBzi3X4qkRNa67Ov1yojxeveYM3a7XJvp495Bi-WwgqmhyRgdYGMEm13v7jpl_23cnx</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>196631895</pqid></control><display><type>article</type><title>Bone marrow histology in marginal zone B-cell lymphomas: correlation with clinical parameters and flow cytometry in 120 patients</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Alma/SFX Local Collection</source><creator>Boveri, E. ; Arcaini, L. ; Merli, M. ; Passamonti, F. ; Rizzi, S. ; Vanelli, L. ; Rumi, E. ; Rattotti, S. ; Lucioni, M. ; Picone, C. ; Castello, A. ; Pascutto, C. ; Magrini, U. ; Lazzarino, M. ; Paulli, M.</creator><creatorcontrib>Boveri, E. ; Arcaini, L. ; Merli, M. ; Passamonti, F. ; Rizzi, S. ; Vanelli, L. ; Rumi, E. ; Rattotti, S. ; Lucioni, M. ; Picone, C. ; Castello, A. ; Pascutto, C. ; Magrini, U. ; Lazzarino, M. ; Paulli, M.</creatorcontrib><description>Background: Among marginal zone lymphomas (MZLs), bone marrow (BM) involvement features are well established in the splenic marginal zone lymphoma (SMZL); few data are available for extranodal marginal zone lymphoma (EMZL) and nodal marginal zone lymphoma (NMZL).
Patients and methods: Incidence and patterns of histologic BM involvement are studied in 120 MZL patients (48 SMZL, 59 EMZL, 13 NMZL) at onset and during follow-up; relationships between clinical features, BM histology and flow cytometry (FC) are analyzed.
Results: At diagnosis, BM involvement occurs in 90% SMZL, 22% EMZL and 54% NMZL (P < 0.0001); at reevaluation, incidence raises to 96% in SMZL and 34% in EMZL. Concordance between histology and FC is found in 87% of cases; most discordant cases have positive histology but negative FC. SMZL and EMZL show a nodular BM infiltration; the interstitial pattern is frequent in NMZL (P < 0.0001); sinusoidal localization is typical of SMZL, frequent in NMZL and occasional in EMZL (P = 0.0001). Stage, leukemic disease, B symptoms, more than one extranodal involved site, splenomegaly, elevated β2-microglobulin, serum monoclonal component, International Prognostic Index (IPI) and age-adjusted IPI are directly related to BM infiltration.
Conclusions: The different prevalence of BM involvement in MZL subtypes reflects their heterogeneous dissemination modalities; histology seems more sensible than FC to detect BM infiltration; development of BM involvement during follow-up is typical of EMZL.</description><identifier>ISSN: 0923-7534</identifier><identifier>EISSN: 1569-8041</identifier><identifier>DOI: 10.1093/annonc/mdn563</identifier><identifier>PMID: 18718888</identifier><language>eng</language><publisher>Oxford: Elsevier Ltd</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Antineoplastic agents ; Biological and medical sciences ; Bone Marrow - pathology ; bone marrow histology ; Bone Marrow Neoplasms - epidemiology ; Bone Marrow Neoplasms - pathology ; Bone Marrow Neoplasms - secondary ; Disease Progression ; Female ; Flow Cytometry ; Follow-Up Studies ; Hematologic and hematopoietic diseases ; hepatitis C virus (HCV) ; Human viral diseases ; Humans ; Incidence ; Infectious diseases ; Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis ; Lymphoma, B-Cell, Marginal Zone - diagnosis ; Lymphoma, B-Cell, Marginal Zone - epidemiology ; Lymphoma, B-Cell, Marginal Zone - pathology ; Male ; marginal zone lymphoma ; Medical sciences ; Middle Aged ; Pharmacology. Drug treatments ; Retrospective Studies ; Viral diseases ; Viral hepatitis</subject><ispartof>Annals of oncology, 2009-01, Vol.20 (1), p.129-136</ispartof><rights>2008 European Society for Medical Oncology</rights><rights>The Author 2008. Published by Oxford University Press on behalf of the European Society for Medical Oncology. All rights reserved. For permissions, please email: journals.permissions@oxfordjournals.org 2009</rights><rights>2009 INIST-CNRS</rights><rights>The Author 2008. Published by Oxford University Press on behalf of the European Society for Medical Oncology. All rights reserved. For permissions, please email: journals.permissions@oxfordjournals.org</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c506t-e46bcb405fa22b40624f1bd5466de9400793eae14ce068258b41ccc50d8a542f3</citedby><cites>FETCH-LOGICAL-c506t-e46bcb405fa22b40624f1bd5466de9400793eae14ce068258b41ccc50d8a542f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=21204930$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18718888$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Boveri, E.</creatorcontrib><creatorcontrib>Arcaini, L.</creatorcontrib><creatorcontrib>Merli, M.</creatorcontrib><creatorcontrib>Passamonti, F.</creatorcontrib><creatorcontrib>Rizzi, S.</creatorcontrib><creatorcontrib>Vanelli, L.</creatorcontrib><creatorcontrib>Rumi, E.</creatorcontrib><creatorcontrib>Rattotti, S.</creatorcontrib><creatorcontrib>Lucioni, M.</creatorcontrib><creatorcontrib>Picone, C.</creatorcontrib><creatorcontrib>Castello, A.</creatorcontrib><creatorcontrib>Pascutto, C.</creatorcontrib><creatorcontrib>Magrini, U.</creatorcontrib><creatorcontrib>Lazzarino, M.</creatorcontrib><creatorcontrib>Paulli, M.</creatorcontrib><title>Bone marrow histology in marginal zone B-cell lymphomas: correlation with clinical parameters and flow cytometry in 120 patients</title><title>Annals of oncology</title><addtitle>Ann Oncol</addtitle><description>Background: Among marginal zone lymphomas (MZLs), bone marrow (BM) involvement features are well established in the splenic marginal zone lymphoma (SMZL); few data are available for extranodal marginal zone lymphoma (EMZL) and nodal marginal zone lymphoma (NMZL).
Patients and methods: Incidence and patterns of histologic BM involvement are studied in 120 MZL patients (48 SMZL, 59 EMZL, 13 NMZL) at onset and during follow-up; relationships between clinical features, BM histology and flow cytometry (FC) are analyzed.
Results: At diagnosis, BM involvement occurs in 90% SMZL, 22% EMZL and 54% NMZL (P < 0.0001); at reevaluation, incidence raises to 96% in SMZL and 34% in EMZL. Concordance between histology and FC is found in 87% of cases; most discordant cases have positive histology but negative FC. SMZL and EMZL show a nodular BM infiltration; the interstitial pattern is frequent in NMZL (P < 0.0001); sinusoidal localization is typical of SMZL, frequent in NMZL and occasional in EMZL (P = 0.0001). Stage, leukemic disease, B symptoms, more than one extranodal involved site, splenomegaly, elevated β2-microglobulin, serum monoclonal component, International Prognostic Index (IPI) and age-adjusted IPI are directly related to BM infiltration.
Conclusions: The different prevalence of BM involvement in MZL subtypes reflects their heterogeneous dissemination modalities; histology seems more sensible than FC to detect BM infiltration; development of BM involvement during follow-up is typical of EMZL.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Antineoplastic agents</subject><subject>Biological and medical sciences</subject><subject>Bone Marrow - pathology</subject><subject>bone marrow histology</subject><subject>Bone Marrow Neoplasms - epidemiology</subject><subject>Bone Marrow Neoplasms - pathology</subject><subject>Bone Marrow Neoplasms - secondary</subject><subject>Disease Progression</subject><subject>Female</subject><subject>Flow Cytometry</subject><subject>Follow-Up Studies</subject><subject>Hematologic and hematopoietic diseases</subject><subject>hepatitis C virus (HCV)</subject><subject>Human viral diseases</subject><subject>Humans</subject><subject>Incidence</subject><subject>Infectious diseases</subject><subject>Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis</subject><subject>Lymphoma, B-Cell, Marginal Zone - diagnosis</subject><subject>Lymphoma, B-Cell, Marginal Zone - epidemiology</subject><subject>Lymphoma, B-Cell, Marginal Zone - pathology</subject><subject>Male</subject><subject>marginal zone lymphoma</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Pharmacology. Drug treatments</subject><subject>Retrospective Studies</subject><subject>Viral diseases</subject><subject>Viral hepatitis</subject><issn>0923-7534</issn><issn>1569-8041</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqF0c-L1DAUB_Agiju7evQqRVC81E2aH228ueOPFQY8qCB7CZn0dSdrm9QkdXc8-aebsWUFQczlQfjkJXlfhB4R_IJgSU-1c96Z06F1XNA7aEW4kGWDGbmLVlhWtKw5ZUfoOMYrjLGQlbyPjkhTkyavFfp55h0Ugw7BXxc7G5Pv_eW-sO6wd2md7osfB3FWGuj7ot8P484POr4sjA8Bep2sd8W1TbvC9NZZkw-MOugBEoRYaNcWXZ9bm33yeS_8bk0qnFGy4FJ8gO51uo_wcKkn6PPbN5_W5-Xmw7v361eb0nAsUglMbM2WYd7pqspVVKwj25YzIVqQDONaUtBAmAEsmoo3W0aMyWfbRnNWdfQEPZv7jsF_myAmNdh4-JN24KeohGgormmV4ZO_4JWfQh5EVEQKQUkjeUbljEzwMQbo1BhsntheEawOuag5FzXnkv3jpem0HaD9o5cgMni6AB3zDLugnbHx1lV5ZExSnN3z2flp_O-dyxtzqnBzi3X4qkRNa67Ov1yojxeveYM3a7XJvp495Bi-WwgqmhyRgdYGMEm13v7jpl_23cnx</recordid><startdate>20090101</startdate><enddate>20090101</enddate><creator>Boveri, E.</creator><creator>Arcaini, L.</creator><creator>Merli, M.</creator><creator>Passamonti, F.</creator><creator>Rizzi, S.</creator><creator>Vanelli, L.</creator><creator>Rumi, E.</creator><creator>Rattotti, S.</creator><creator>Lucioni, M.</creator><creator>Picone, C.</creator><creator>Castello, A.</creator><creator>Pascutto, C.</creator><creator>Magrini, U.</creator><creator>Lazzarino, M.</creator><creator>Paulli, M.</creator><general>Elsevier Ltd</general><general>Oxford University Press</general><general>Oxford Publishing Limited (England)</general><scope>6I.</scope><scope>AAFTH</scope><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7TM</scope><scope>7TO</scope><scope>H94</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>20090101</creationdate><title>Bone marrow histology in marginal zone B-cell lymphomas: correlation with clinical parameters and flow cytometry in 120 patients</title><author>Boveri, E. ; Arcaini, L. ; Merli, M. ; Passamonti, F. ; Rizzi, S. ; Vanelli, L. ; Rumi, E. ; Rattotti, S. ; Lucioni, M. ; Picone, C. ; Castello, A. ; Pascutto, C. ; Magrini, U. ; Lazzarino, M. ; Paulli, M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c506t-e46bcb405fa22b40624f1bd5466de9400793eae14ce068258b41ccc50d8a542f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Antineoplastic agents</topic><topic>Biological and medical sciences</topic><topic>Bone Marrow - pathology</topic><topic>bone marrow histology</topic><topic>Bone Marrow Neoplasms - epidemiology</topic><topic>Bone Marrow Neoplasms - pathology</topic><topic>Bone Marrow Neoplasms - secondary</topic><topic>Disease Progression</topic><topic>Female</topic><topic>Flow Cytometry</topic><topic>Follow-Up Studies</topic><topic>Hematologic and hematopoietic diseases</topic><topic>hepatitis C virus (HCV)</topic><topic>Human viral diseases</topic><topic>Humans</topic><topic>Incidence</topic><topic>Infectious diseases</topic><topic>Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis</topic><topic>Lymphoma, B-Cell, Marginal Zone - diagnosis</topic><topic>Lymphoma, B-Cell, Marginal Zone - epidemiology</topic><topic>Lymphoma, B-Cell, Marginal Zone - pathology</topic><topic>Male</topic><topic>marginal zone lymphoma</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Pharmacology. Drug treatments</topic><topic>Retrospective Studies</topic><topic>Viral diseases</topic><topic>Viral hepatitis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Boveri, E.</creatorcontrib><creatorcontrib>Arcaini, L.</creatorcontrib><creatorcontrib>Merli, M.</creatorcontrib><creatorcontrib>Passamonti, F.</creatorcontrib><creatorcontrib>Rizzi, S.</creatorcontrib><creatorcontrib>Vanelli, L.</creatorcontrib><creatorcontrib>Rumi, E.</creatorcontrib><creatorcontrib>Rattotti, S.</creatorcontrib><creatorcontrib>Lucioni, M.</creatorcontrib><creatorcontrib>Picone, C.</creatorcontrib><creatorcontrib>Castello, A.</creatorcontrib><creatorcontrib>Pascutto, C.</creatorcontrib><creatorcontrib>Magrini, U.</creatorcontrib><creatorcontrib>Lazzarino, M.</creatorcontrib><creatorcontrib>Paulli, M.</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Annals of oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Boveri, E.</au><au>Arcaini, L.</au><au>Merli, M.</au><au>Passamonti, F.</au><au>Rizzi, S.</au><au>Vanelli, L.</au><au>Rumi, E.</au><au>Rattotti, S.</au><au>Lucioni, M.</au><au>Picone, C.</au><au>Castello, A.</au><au>Pascutto, C.</au><au>Magrini, U.</au><au>Lazzarino, M.</au><au>Paulli, M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Bone marrow histology in marginal zone B-cell lymphomas: correlation with clinical parameters and flow cytometry in 120 patients</atitle><jtitle>Annals of oncology</jtitle><addtitle>Ann Oncol</addtitle><date>2009-01-01</date><risdate>2009</risdate><volume>20</volume><issue>1</issue><spage>129</spage><epage>136</epage><pages>129-136</pages><issn>0923-7534</issn><eissn>1569-8041</eissn><abstract>Background: Among marginal zone lymphomas (MZLs), bone marrow (BM) involvement features are well established in the splenic marginal zone lymphoma (SMZL); few data are available for extranodal marginal zone lymphoma (EMZL) and nodal marginal zone lymphoma (NMZL).
Patients and methods: Incidence and patterns of histologic BM involvement are studied in 120 MZL patients (48 SMZL, 59 EMZL, 13 NMZL) at onset and during follow-up; relationships between clinical features, BM histology and flow cytometry (FC) are analyzed.
Results: At diagnosis, BM involvement occurs in 90% SMZL, 22% EMZL and 54% NMZL (P < 0.0001); at reevaluation, incidence raises to 96% in SMZL and 34% in EMZL. Concordance between histology and FC is found in 87% of cases; most discordant cases have positive histology but negative FC. SMZL and EMZL show a nodular BM infiltration; the interstitial pattern is frequent in NMZL (P < 0.0001); sinusoidal localization is typical of SMZL, frequent in NMZL and occasional in EMZL (P = 0.0001). Stage, leukemic disease, B symptoms, more than one extranodal involved site, splenomegaly, elevated β2-microglobulin, serum monoclonal component, International Prognostic Index (IPI) and age-adjusted IPI are directly related to BM infiltration.
Conclusions: The different prevalence of BM involvement in MZL subtypes reflects their heterogeneous dissemination modalities; histology seems more sensible than FC to detect BM infiltration; development of BM involvement during follow-up is typical of EMZL.</abstract><cop>Oxford</cop><pub>Elsevier Ltd</pub><pmid>18718888</pmid><doi>10.1093/annonc/mdn563</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0923-7534 |
| ispartof | Annals of oncology, 2009-01, Vol.20 (1), p.129-136 |
| issn | 0923-7534 1569-8041 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_66830732 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Adult Aged Aged, 80 and over Antineoplastic agents Biological and medical sciences Bone Marrow - pathology bone marrow histology Bone Marrow Neoplasms - epidemiology Bone Marrow Neoplasms - pathology Bone Marrow Neoplasms - secondary Disease Progression Female Flow Cytometry Follow-Up Studies Hematologic and hematopoietic diseases hepatitis C virus (HCV) Human viral diseases Humans Incidence Infectious diseases Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymphoma, B-Cell, Marginal Zone - diagnosis Lymphoma, B-Cell, Marginal Zone - epidemiology Lymphoma, B-Cell, Marginal Zone - pathology Male marginal zone lymphoma Medical sciences Middle Aged Pharmacology. Drug treatments Retrospective Studies Viral diseases Viral hepatitis |
| title | Bone marrow histology in marginal zone B-cell lymphomas: correlation with clinical parameters and flow cytometry in 120 patients |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-18T09%3A42%3A44IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Bone%20marrow%20histology%20in%20marginal%20zone%20B-cell%20lymphomas:%20correlation%20with%20clinical%20parameters%20and%20flow%20cytometry%20in%20120%20patients&rft.jtitle=Annals%20of%20oncology&rft.au=Boveri,%20E.&rft.date=2009-01-01&rft.volume=20&rft.issue=1&rft.spage=129&rft.epage=136&rft.pages=129-136&rft.issn=0923-7534&rft.eissn=1569-8041&rft_id=info:doi/10.1093/annonc/mdn563&rft_dat=%3Cproquest_cross%3E1631051241%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=196631895&rft_id=info:pmid/18718888&rft_oup_id=10.1093/annonc/mdn563&rft_els_id=S0923753419399715&rfr_iscdi=true |