SPCA1 pumps and Hailey–Hailey disease

Both the endoplasmic reticulum and the Golgi apparatus are agonist-sensitive intracellular Ca 2+ stores. The Golgi apparatus has Ca 2+-release channels and a Ca 2+-uptake mechanism consisting of sarco(endo)plasmic-reticulum Ca 2+-ATPases (SERCA) and secretory-pathway Ca 2+-ATPases (SPCA). SPCA1 has...

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Veröffentlicht in:	Biochemical and biophysical research communications 2004-10, Vol.322 (4), p.1204-1213
Hauptverfasser:	Missiaen, Ludwig, Raeymaekers, Luc, Dode, Leonard, Vanoevelen, Jo, Van Baelen, Kurt, Parys, Jan B., Callewaert, Geert, De Smedt, Humbert, Segaert, Siegfried, Wuytack, Frank
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Animals Calcium - metabolism Calcium pump Calcium store Calcium-Transporting ATPases - genetics Calcium-Transporting ATPases - physiology Dermatology Female Golgi apparatus Golgi Apparatus - enzymology Hailey–Hailey disease Humans Intracellular calcium Manganese - metabolism Pemphigus, Benign Familial - enzymology Pemphigus, Benign Familial - genetics Pemphigus, Benign Familial - pathology Secretory pathway
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