Effects of extracellular calcium on the growth-differentiation switch in immortalized keratinocyte HaCaT cells compared with normal human keratinocytes

: The keratinocyte growth and differentiation switch, tightly regulated by several mechanisms, is generally associated with decreased proliferation, cell cycle arrest in G0/G1 phase and expression of epidermal differentiation markers, such as keratin 1 (K1), keratin 10 (K10) and involucrin. In vitr...

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Veröffentlicht in:	Experimental dermatology 2009-02, Vol.18 (2), p.143-151
Hauptverfasser:	Micallef, Ludovic, Belaubre, Françoise, Pinon, Aline, Jayat-Vignoles, Chantal, Delage, Christiane, Charveron, Marie, Simon, Alain
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Biomarkers - metabolism calcium Calcium - physiology Cell Cycle - drug effects Cell Differentiation Cell Line Cell Proliferation Cells, Cultured Dermatology differentiation HaCaT Humans Keratin-1 - metabolism Keratin-10 - metabolism Keratinocytes - cytology Keratinocytes - metabolism Medical sciences normal human keratinocytes proliferation Protein Precursors - metabolism
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