Predicting Progression — ZAP-70 in CLL

The harder we look, the more we find. Diagnoses of chronic lymphocytic leukemia (CLL) are becoming more common because we are looking harder. With sensitive techniques, a monoclonal population of B lymphocytes that is indistinguishable from CLL cells may be found in the blood of 3.5 percent of perso...

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Veröffentlicht in:	The New England journal of medicine 2004-08, Vol.351 (9), p.856-857
1. Verfasser:	Hamblin, Terry J
Format:	Artikel
Sprache:	eng
Schlagworte:	B-Lymphocytes - metabolism Binding sites Biological and medical sciences Disease Progression General aspects Genes, Immunoglobulin Hematologic and hematopoietic diseases Immune system Immunoglobulin Heavy Chains - genetics Immunology Leukemia, Lymphocytic, Chronic, B-Cell - genetics Leukemia, Lymphocytic, Chronic, B-Cell - metabolism Leukemia, Lymphocytic, Chronic, B-Cell - therapy Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymphocytes Medical research Medical sciences Mutation Protein-Tyrosine Kinases - metabolism Receptors, Antigen, T-Cell Signal Transduction T-Lymphocytes - metabolism ZAP-70 Protein-Tyrosine Kinase
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