PTENless means more

Recent studies indicate that certain key molecules that are vital for various developmental processes, such as Wnt, Shh, and Notch, cause cancer when dysregulated. PTEN, a tumor suppressor that antagonizes the PI3 kinase pathway, is the newest one on the list. The biological function of PTEN is evol...

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Veröffentlicht in:	Developmental biology 2004-09, Vol.273 (2), p.175-184
Hauptverfasser:	Stiles, Bangyan, Groszer, Matthias, Wang, Shunyou, Jiao, Jing, Wu, Hong
Format:	Artikel
Sprache:	eng
Schlagworte:	AKT Animals Cell Movement Embryonic and Fetal Development - genetics Embryonic and Fetal Development - physiology Female Gene Expression Regulation, Developmental Hormone Hormones - physiology Humans Male Mice Migration Models, Biological Organ size Protein Tyrosine Phosphatases - deficiency Protein Tyrosine Phosphatases - genetics Protein Tyrosine Phosphatases - physiology PTEN PTEN Phosphohydrolase Signal Transduction Stem cells Stem Cells - cytology Stem Cells - physiology Tumor Suppressor Proteins - deficiency Tumor Suppressor Proteins - genetics Tumor Suppressor Proteins - physiology
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