Effects of different corticosteroids on the brain weight and hippocampal neuronal loss in rats

Abstract Equivalent antiinflammatory doses of steroids including betamethasone, methylprednisolone and dexamethasone were administered in the neonatal period in a rat model. In situ cell death in hippocampus quantified by Terminal Deoxynucleated Transferase Nick-End Labeling and on ratio of brain to...

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Veröffentlicht in:	Brain research 2009-01, Vol.1250, p.75-80
Hauptverfasser:	Duksal, Fatma, Kilic, Ilknur, Tufan, A.Cevik, Akdogan, Ilgaz
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Cortex Hormones - pharmacology Analysis of Variance Animals Apoptosis - drug effects Betamethasone Betamethasone - pharmacology Biological and medical sciences Body Weight Bones, joints and connective tissue. Antiinflammatory agents Brain - anatomy & histology Brain - drug effects Cell Death - drug effects Dexamethasone Dexamethasone - pharmacology Hippocampus - drug effects Hippocampus - physiology In Situ Nick-End Labeling Male Medical sciences Methylprednisolone Methylprednisolone - pharmacology Neurology Neurons - drug effects Neurons - physiology Organ Size - drug effects Pharmacology. Drug treatments Premature Rats Rats, Sprague-Dawley TUNEL positive neuron
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