Evaluation of analgesic and anti-inflammatory activities of Nectandra megapotamica (Lauraceae) in mice and rats

The bioactivity‐guided phytochemical investigation of the crude hydralcoholic extract of Nectandra megapotamica was carried out using the abdominal constriction test in mice, which led to the isolation of three active compounds: α‐asarone (1), galgravin (2) and veraguensin (3). The crude extract (EB...

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Veröffentlicht in:	Journal of pharmacy and pharmacology 2004-09, Vol.56 (9), p.1179-1184
Hauptverfasser:	Filho, Ademar A. da Silva, Silva, Márcio L. Andrade e, Carvalho, José Carlos T., Bastos, Jairo K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analgesics - chemistry Analgesics - isolation & purification Analgesics - pharmacology Animals Anti-Inflammatory Agents, Non-Steroidal - chemistry Anti-Inflammatory Agents, Non-Steroidal - isolation & purification Anti-Inflammatory Agents, Non-Steroidal - pharmacology Dose-Response Relationship, Drug Drug Evaluation, Preclinical - methods Lauraceae Male Mice Pain Measurement - drug effects Pain Measurement - methods Plant Bark Plant Extracts - chemistry Plant Extracts - isolation & purification Plant Extracts - pharmacology Rats Rats, Wistar
Online-Zugang:	Volltext
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