Feasibility of assessment of coronary stent patency using 16-slice computed tomography
Intracoronary stent implantation is a frequently performed procedure in the treatment of stenoses in coronary arteries, but in-stent restenosis occurs in ∼10% to 15% of patients. A noninvasive diagnostic procedure to evaluate in-stent restenosis would therefore be of great benefit. We investigated t...
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Veröffentlicht in: | The American journal of cardiology 2004-08, Vol.94 (4), p.427-430 |
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creator | Schuijf, Joanne D. Bax, Jeroen J. Jukema, J.Wouter Lamb, Hildo J. Warda, Hazem M.A. Vliegen, Hubert W. de Roos, Albert van der Wall, Ernst E. |
description | Intracoronary stent implantation is a frequently performed procedure in the treatment of stenoses in coronary arteries, but in-stent restenosis occurs in ∼10% to 15% of patients. A noninvasive diagnostic procedure to evaluate in-stent restenosis would therefore be of great benefit. We investigated the feasibility of assessing stent patency with 16-slice computed tomography. Multislice computed tomography (MSCT) was performed in 22 patients with previously implanted stents. For each stent, assessability was determined and related to stent type and diameter. Subsequently, the presence of significant restenosis was determined in the evaluable stents. In addition, peristent lumina (5 mm proximal and distal to the stent) were evaluated. Conventional angiography in combination with quantitative coronary angiography served as the standard of reference. MSCT was performed successfully in all but 1 patient. Of 65 stents, 50 (77%) were determined assessable. Uninterpretable stents tended to have a thicker strut and/or a smaller diameter. In the evaluable stents, 7 of 9 stenoses were detected and the absence of restenosis was correctly identified in all 41 patent stents, resulting in a sensitivity and specificity of 78% and 100%, respectively. Sensitivity and specificity for the detection of peristent stenosis were 75% and 96%, respectively. In conclusion, MSCT may be useful in the assessment of stent patency and may function as a gatekeeper before invasive diagnostic procedures. |
doi_str_mv | 10.1016/j.amjcard.2004.04.057 |
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A noninvasive diagnostic procedure to evaluate in-stent restenosis would therefore be of great benefit. We investigated the feasibility of assessing stent patency with 16-slice computed tomography. Multislice computed tomography (MSCT) was performed in 22 patients with previously implanted stents. For each stent, assessability was determined and related to stent type and diameter. Subsequently, the presence of significant restenosis was determined in the evaluable stents. In addition, peristent lumina (5 mm proximal and distal to the stent) were evaluated. Conventional angiography in combination with quantitative coronary angiography served as the standard of reference. MSCT was performed successfully in all but 1 patient. Of 65 stents, 50 (77%) were determined assessable. Uninterpretable stents tended to have a thicker strut and/or a smaller diameter. In the evaluable stents, 7 of 9 stenoses were detected and the absence of restenosis was correctly identified in all 41 patent stents, resulting in a sensitivity and specificity of 78% and 100%, respectively. Sensitivity and specificity for the detection of peristent stenosis were 75% and 96%, respectively. In conclusion, MSCT may be useful in the assessment of stent patency and may function as a gatekeeper before invasive diagnostic procedures.</description><identifier>ISSN: 0002-9149</identifier><identifier>EISSN: 1879-1913</identifier><identifier>DOI: 10.1016/j.amjcard.2004.04.057</identifier><identifier>PMID: 15325923</identifier><identifier>CODEN: AJCDAG</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Aged ; Angiography ; Angioplasty, Balloon, Coronary - instrumentation ; Biological and medical sciences ; Cardiology ; Cardiology. Vascular system ; Coronary Angiography ; Coronary heart disease ; Coronary Restenosis - diagnostic imaging ; Coronary Stenosis - diagnostic imaging ; Coronary Stenosis - therapy ; Diagnostics ; Feasibility studies ; Female ; Follow-Up Studies ; Heart ; Humans ; Image Processing, Computer-Assisted ; Imaging, Three-Dimensional ; Male ; Medical sciences ; Middle Aged ; Myocardial Infarction - diagnostic imaging ; Myocardial Infarction - therapy ; Prosthesis Failure ; Recurrence ; Sensitivity and Specificity ; Stents ; Tomography ; Tomography, Spiral Computed</subject><ispartof>The American journal of cardiology, 2004-08, Vol.94 (4), p.427-430</ispartof><rights>2004 Excerpta Medica Inc.</rights><rights>2004 INIST-CNRS</rights><rights>Copyright Elsevier Sequoia S.A. 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A noninvasive diagnostic procedure to evaluate in-stent restenosis would therefore be of great benefit. We investigated the feasibility of assessing stent patency with 16-slice computed tomography. Multislice computed tomography (MSCT) was performed in 22 patients with previously implanted stents. For each stent, assessability was determined and related to stent type and diameter. Subsequently, the presence of significant restenosis was determined in the evaluable stents. In addition, peristent lumina (5 mm proximal and distal to the stent) were evaluated. Conventional angiography in combination with quantitative coronary angiography served as the standard of reference. MSCT was performed successfully in all but 1 patient. Of 65 stents, 50 (77%) were determined assessable. Uninterpretable stents tended to have a thicker strut and/or a smaller diameter. In the evaluable stents, 7 of 9 stenoses were detected and the absence of restenosis was correctly identified in all 41 patent stents, resulting in a sensitivity and specificity of 78% and 100%, respectively. Sensitivity and specificity for the detection of peristent stenosis were 75% and 96%, respectively. In conclusion, MSCT may be useful in the assessment of stent patency and may function as a gatekeeper before invasive diagnostic procedures.</description><subject>Aged</subject><subject>Angiography</subject><subject>Angioplasty, Balloon, Coronary - instrumentation</subject><subject>Biological and medical sciences</subject><subject>Cardiology</subject><subject>Cardiology. Vascular system</subject><subject>Coronary Angiography</subject><subject>Coronary heart disease</subject><subject>Coronary Restenosis - diagnostic imaging</subject><subject>Coronary Stenosis - diagnostic imaging</subject><subject>Coronary Stenosis - therapy</subject><subject>Diagnostics</subject><subject>Feasibility studies</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Heart</subject><subject>Humans</subject><subject>Image Processing, Computer-Assisted</subject><subject>Imaging, Three-Dimensional</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Myocardial Infarction - diagnostic imaging</subject><subject>Myocardial Infarction - therapy</subject><subject>Prosthesis Failure</subject><subject>Recurrence</subject><subject>Sensitivity and Specificity</subject><subject>Stents</subject><subject>Tomography</subject><subject>Tomography, Spiral Computed</subject><issn>0002-9149</issn><issn>1879-1913</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkF-L1TAQxYMo7nX1IyhF0Ldek-b_kyyLq8KCL-pryE2na0rb1Ewr3G9vyi0s-CIMDDP85jDnEPKa0SOjTH3oj37sg8_tsaFUHLeS-gk5MKNtzSzjT8mBUtrUlgl7RV4g9mVkTKrn5IpJ3kjb8AP5eQce4ykOcTlXqas8IiCOMC3bFFJOk8_nCpdtM_vSwrlaMU4PFVM1DjFAocZ5XaCtljSmh-znX-eX5FnnB4RXe78mP-4-fb_9Ut9_-_z19ua-DsKIpbaKWeu10oJ2utOgdQgGOt5yT8FQzYW1rWIyNIyJk5RKGGNl8W-gzMXANXl_0Z1z-r0CLm6MGGAY_ARpRadUUaHCFvDtP2Cf1jyV31zDKZdGGV4geYFCTogZOjfnOBb_jlG3pe56t6futtTdVlKXuze7-HoaoX282mMuwLsd8Bj80GU_hYiPnKJKWrUJfbxwUDL7EyE7DLFEDm3MEBbXpvifV_4C2j-hXA</recordid><startdate>20040815</startdate><enddate>20040815</enddate><creator>Schuijf, Joanne D.</creator><creator>Bax, Jeroen J.</creator><creator>Jukema, J.Wouter</creator><creator>Lamb, Hildo J.</creator><creator>Warda, Hazem M.A.</creator><creator>Vliegen, Hubert W.</creator><creator>de Roos, Albert</creator><creator>van der Wall, Ernst E.</creator><general>Elsevier Inc</general><general>Elsevier</general><general>Elsevier Limited</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TS</scope><scope>8FD</scope><scope>FR3</scope><scope>K9.</scope><scope>M7Z</scope><scope>NAPCQ</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>20040815</creationdate><title>Feasibility of assessment of coronary stent patency using 16-slice computed tomography</title><author>Schuijf, Joanne D. ; Bax, Jeroen J. ; Jukema, J.Wouter ; Lamb, Hildo J. ; Warda, Hazem M.A. ; Vliegen, Hubert W. ; de Roos, Albert ; van der Wall, Ernst E.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c484t-96199a76740f7f7e77cc8ef3d3a0e8073499d615c2114b556488951018e14b923</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Aged</topic><topic>Angiography</topic><topic>Angioplasty, Balloon, Coronary - instrumentation</topic><topic>Biological and medical sciences</topic><topic>Cardiology</topic><topic>Cardiology. Vascular system</topic><topic>Coronary Angiography</topic><topic>Coronary heart disease</topic><topic>Coronary Restenosis - diagnostic imaging</topic><topic>Coronary Stenosis - diagnostic imaging</topic><topic>Coronary Stenosis - therapy</topic><topic>Diagnostics</topic><topic>Feasibility studies</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Heart</topic><topic>Humans</topic><topic>Image Processing, Computer-Assisted</topic><topic>Imaging, Three-Dimensional</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Myocardial Infarction - diagnostic imaging</topic><topic>Myocardial Infarction - therapy</topic><topic>Prosthesis Failure</topic><topic>Recurrence</topic><topic>Sensitivity and Specificity</topic><topic>Stents</topic><topic>Tomography</topic><topic>Tomography, Spiral Computed</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Schuijf, Joanne D.</creatorcontrib><creatorcontrib>Bax, Jeroen J.</creatorcontrib><creatorcontrib>Jukema, J.Wouter</creatorcontrib><creatorcontrib>Lamb, Hildo J.</creatorcontrib><creatorcontrib>Warda, Hazem M.A.</creatorcontrib><creatorcontrib>Vliegen, Hubert W.</creatorcontrib><creatorcontrib>de Roos, Albert</creatorcontrib><creatorcontrib>van der Wall, Ernst E.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Physical Education Index</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biochemistry Abstracts 1</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Schuijf, Joanne D.</au><au>Bax, Jeroen J.</au><au>Jukema, J.Wouter</au><au>Lamb, Hildo J.</au><au>Warda, Hazem M.A.</au><au>Vliegen, Hubert W.</au><au>de Roos, Albert</au><au>van der Wall, Ernst E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Feasibility of assessment of coronary stent patency using 16-slice computed tomography</atitle><jtitle>The American journal of cardiology</jtitle><addtitle>Am J Cardiol</addtitle><date>2004-08-15</date><risdate>2004</risdate><volume>94</volume><issue>4</issue><spage>427</spage><epage>430</epage><pages>427-430</pages><issn>0002-9149</issn><eissn>1879-1913</eissn><coden>AJCDAG</coden><abstract>Intracoronary stent implantation is a frequently performed procedure in the treatment of stenoses in coronary arteries, but in-stent restenosis occurs in ∼10% to 15% of patients. A noninvasive diagnostic procedure to evaluate in-stent restenosis would therefore be of great benefit. We investigated the feasibility of assessing stent patency with 16-slice computed tomography. Multislice computed tomography (MSCT) was performed in 22 patients with previously implanted stents. For each stent, assessability was determined and related to stent type and diameter. Subsequently, the presence of significant restenosis was determined in the evaluable stents. In addition, peristent lumina (5 mm proximal and distal to the stent) were evaluated. Conventional angiography in combination with quantitative coronary angiography served as the standard of reference. MSCT was performed successfully in all but 1 patient. Of 65 stents, 50 (77%) were determined assessable. Uninterpretable stents tended to have a thicker strut and/or a smaller diameter. In the evaluable stents, 7 of 9 stenoses were detected and the absence of restenosis was correctly identified in all 41 patent stents, resulting in a sensitivity and specificity of 78% and 100%, respectively. Sensitivity and specificity for the detection of peristent stenosis were 75% and 96%, respectively. In conclusion, MSCT may be useful in the assessment of stent patency and may function as a gatekeeper before invasive diagnostic procedures.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>15325923</pmid><doi>10.1016/j.amjcard.2004.04.057</doi><tpages>4</tpages></addata></record> |
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subjects | Aged Angiography Angioplasty, Balloon, Coronary - instrumentation Biological and medical sciences Cardiology Cardiology. Vascular system Coronary Angiography Coronary heart disease Coronary Restenosis - diagnostic imaging Coronary Stenosis - diagnostic imaging Coronary Stenosis - therapy Diagnostics Feasibility studies Female Follow-Up Studies Heart Humans Image Processing, Computer-Assisted Imaging, Three-Dimensional Male Medical sciences Middle Aged Myocardial Infarction - diagnostic imaging Myocardial Infarction - therapy Prosthesis Failure Recurrence Sensitivity and Specificity Stents Tomography Tomography, Spiral Computed |
title | Feasibility of assessment of coronary stent patency using 16-slice computed tomography |
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