Mechanism of Iodide/Chloride Exchange by Pendrin

We performed an electrophysiological study to investigate ion transport of pendrin and thereby understand the pathogenesis of Pendred syndrome. Using pendrin-transfected COS-7 cells, we could show that pendrin transports both iodide and chloride measured as voltage-dependent inward and outward membr...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Endocrinology (Philadelphia) 2004-09, Vol.145 (9), p.4301-4308
Hauptverfasser:	Yoshida, Akio, Hisatome, Ichiro, Taniguchi, Shinichi, Sasaki, Norihiro, Yamamoto, Yasutaka, Miake, Junichiro, Fukui, Hiroko, Shimizu, Hideki, Okamura, Tomohisa, Okura, Tsuyoshi, Igawa, Osamu, Shigemasa, Chiaki, Green, Eric D, Kohn, Leonard D, Suzuki, Koichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anion exchange Anion exchanging Anions Anions - metabolism Biological and medical sciences Carrier Proteins - genetics Carrier Proteins - metabolism Cell culture Cell membranes Chloride Chloride currents Chloride transport Chlorides Chlorides - pharmacokinetics COS Cells Cytoplasm - metabolism Efflux Electrophysiological recording Fundamental and applied biological sciences. Psychology Humans Iodides Iodides - pharmacokinetics Ion transport Membrane currents Membrane Potentials - physiology Membrane Transport Proteins Patch-Clamp Techniques Pathogenesis Thyroid Transfection Vertebrates: endocrinology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!