Focus on CaMKII: a molecular switch in the pathophysiology and treatment of mood and anxiety disorders

Mood and anxiety disorders are common, severe, chronic, and often life-threatening illnesses (Kaufman and Charney, 2000; Manji et al., 2001). There is a growing appreciation that, far from being diseases with purely psychological manifestations, severe mood and anxiety disorders are systemic disease...

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Veröffentlicht in:	The international journal of neuropsychopharmacology 2004-09, Vol.7 (3), p.243-248
Hauptverfasser:	Du, Jing, Szabo, Steven T., Gray, Neil A., Manji, Husseini K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antidepressive Agents - pharmacology Anxiety Anxiety - genetics Anxiety - physiopathology Calcium-Calmodulin-Dependent Protein Kinase Type 2 Calcium-Calmodulin-Dependent Protein Kinases - genetics Calcium-Calmodulin-Dependent Protein Kinases - physiology Focus Glutamic Acid - physiology Humans Mood Disorders - genetics Mood Disorders - physiopathology Neuronal Plasticity - physiology Signal Transduction - physiology
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