Anti-tumour therapeutic efficacy of OX40L in murine tumour model

OX40 ligand (OX40L), a member of TNF superfamily, is a co-stimulatory molecule involved in T cell activation. Systemic administration of mOX40L fusion protein significantly inhibited the growth of experimental lung metastasis and subcutaneous (s.c.) established colon (CT26) and breast (4T1) carcinom...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Vaccine 2004-09, Vol.22 (27), p.3585-3594
Hauptverfasser:	Ali, Selman A., Ahmad, Murrium, Lynam, June, McLean, Cornelia S., Entwisle, Claire, Loudon, Peter, Choolun, Esther, McArdle, Stephanie E.B., Li, Geng, Mian, Shahid, Rees, Robert C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic Agents - administration & dosage Antineoplastic Agents - therapeutic use Applied microbiology Biological and medical sciences Cancer Cancer Vaccines - therapeutic use CD4-Positive T-Lymphocytes - immunology CD8-Positive T-Lymphocytes - immunology Cell Division - drug effects Cell growth Cell Line Cell Line, Tumor CTL Cytokines Female Fundamental and applied biological sciences. Psychology Granulocyte-Macrophage Colony-Stimulating Factor - metabolism Immunotherapy Injections, Intraperitoneal Ligands Lymphocytes Medical sciences Membrane Glycoproteins - administration & dosage Membrane Glycoproteins - therapeutic use Metastasis Mice Mice, Inbred BALB C Microbiology Neoplasm Transplantation Neoplasms, Experimental - immunology Neoplasms, Experimental - therapy OX40L Peptides Proteins Rodents Simplexvirus - genetics Simplexvirus - immunology Spleen - cytology Spleen - immunology T cell receptors T-Lymphocytes, Cytotoxic - immunology Tumor Necrosis Factors Tumors Vaccination Vaccines Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!