Oral histoplasmosis associated with HIV infection: a comparative study

Objective:  Histoplasmosis is a granulomatous fungal disease caused by Histoplasma capsulatum. The objective of the present paper was to describe the prevalence of oral histoplasmosis (OH) in two services from an endemic area in Argentina between 1991 and 2002 and to compare the clinicopathological...

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Veröffentlicht in:Journal of oral pathology & medicine 2004-09, Vol.33 (8), p.445-450
Hauptverfasser: Hernández, S. L., López de Blanc, S. A., Sambuelli, R. H., Roland, H., Cornelli, C., Lattanzi, V., Carnelli, M. A.
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container_end_page 450
container_issue 8
container_start_page 445
container_title Journal of oral pathology & medicine
container_volume 33
creator Hernández, S. L.
López de Blanc, S. A.
Sambuelli, R. H.
Roland, H.
Cornelli, C.
Lattanzi, V.
Carnelli, M. A.
description Objective:  Histoplasmosis is a granulomatous fungal disease caused by Histoplasma capsulatum. The objective of the present paper was to describe the prevalence of oral histoplasmosis (OH) in two services from an endemic area in Argentina between 1991 and 2002 and to compare the clinicopathological profile of OH between HIV‐positive and HIV‐negative patients. Methods:  About 733 HIV+ (group A) and 14 260 patients (group B) were examined. Clinical diagnosis was confirmed by cytology, biopsy or culture. Results:  About 21 (3%) and 10 (0.07%) cases of OH were diagnosed in group A and B respectively. Most patients were male. A total of 90% of patients in group A were
doi_str_mv 10.1111/j.1600-0714.2004.00200.x-i1
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L. ; López de Blanc, S. A. ; Sambuelli, R. H. ; Roland, H. ; Cornelli, C. ; Lattanzi, V. ; Carnelli, M. A.</creator><creatorcontrib>Hernández, S. L. ; López de Blanc, S. A. ; Sambuelli, R. H. ; Roland, H. ; Cornelli, C. ; Lattanzi, V. ; Carnelli, M. A.</creatorcontrib><description>Objective:  Histoplasmosis is a granulomatous fungal disease caused by Histoplasma capsulatum. The objective of the present paper was to describe the prevalence of oral histoplasmosis (OH) in two services from an endemic area in Argentina between 1991 and 2002 and to compare the clinicopathological profile of OH between HIV‐positive and HIV‐negative patients. Methods:  About 733 HIV+ (group A) and 14 260 patients (group B) were examined. Clinical diagnosis was confirmed by cytology, biopsy or culture. Results:  About 21 (3%) and 10 (0.07%) cases of OH were diagnosed in group A and B respectively. Most patients were male. A total of 90% of patients in group A were &lt;45 years old whereas 70% of group B were more than 45 years old. Palate, gingiva and oropharynx were the most frequent locations. The importance of including histoplasmosis in the differential diagnosis of ulcerated oral lesions in immunocompromised patients was discussed.</description><identifier>ISSN: 0904-2512</identifier><identifier>EISSN: 1600-0714</identifier><identifier>DOI: 10.1111/j.1600-0714.2004.00200.x-i1</identifier><identifier>PMID: 15315479</identifier><language>eng</language><publisher>Oxford, UK: Munksgaard International Publishers</publisher><subject>Adult ; Age Factors ; Aged ; AIDS-Related Opportunistic Infections - epidemiology ; Argentina - epidemiology ; Biological and medical sciences ; Dentistry ; Diagnosis, Differential ; Endemic Diseases ; Female ; Gingival Diseases - epidemiology ; Gingival Diseases - microbiology ; Histoplasmoses ; histoplasmosis ; Histoplasmosis - epidemiology ; HIV Infections - epidemiology ; HIV Seronegativity ; human immunodeficiency virus ; Human mycoses ; Humans ; Immunocompromised Host ; Infectious diseases ; Male ; Medical sciences ; Middle Aged ; Mouth Diseases - epidemiology ; Mouth Diseases - microbiology ; Mycoses ; oral histoplasmosis ; Oropharynx - microbiology ; Otorhinolaryngology. 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L.</creatorcontrib><creatorcontrib>López de Blanc, S. A.</creatorcontrib><creatorcontrib>Sambuelli, R. H.</creatorcontrib><creatorcontrib>Roland, H.</creatorcontrib><creatorcontrib>Cornelli, C.</creatorcontrib><creatorcontrib>Lattanzi, V.</creatorcontrib><creatorcontrib>Carnelli, M. A.</creatorcontrib><title>Oral histoplasmosis associated with HIV infection: a comparative study</title><title>Journal of oral pathology &amp; medicine</title><addtitle>J Oral Pathol Med</addtitle><description>Objective:  Histoplasmosis is a granulomatous fungal disease caused by Histoplasma capsulatum. The objective of the present paper was to describe the prevalence of oral histoplasmosis (OH) in two services from an endemic area in Argentina between 1991 and 2002 and to compare the clinicopathological profile of OH between HIV‐positive and HIV‐negative patients. Methods:  About 733 HIV+ (group A) and 14 260 patients (group B) were examined. Clinical diagnosis was confirmed by cytology, biopsy or culture. Results:  About 21 (3%) and 10 (0.07%) cases of OH were diagnosed in group A and B respectively. Most patients were male. A total of 90% of patients in group A were &lt;45 years old whereas 70% of group B were more than 45 years old. Palate, gingiva and oropharynx were the most frequent locations. 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source MEDLINE; Wiley Online Library Journals Frontfile Complete
subjects Adult
Age Factors
Aged
AIDS-Related Opportunistic Infections - epidemiology
Argentina - epidemiology
Biological and medical sciences
Dentistry
Diagnosis, Differential
Endemic Diseases
Female
Gingival Diseases - epidemiology
Gingival Diseases - microbiology
Histoplasmoses
histoplasmosis
Histoplasmosis - epidemiology
HIV Infections - epidemiology
HIV Seronegativity
human immunodeficiency virus
Human mycoses
Humans
Immunocompromised Host
Infectious diseases
Male
Medical sciences
Middle Aged
Mouth Diseases - epidemiology
Mouth Diseases - microbiology
Mycoses
oral histoplasmosis
Oropharynx - microbiology
Otorhinolaryngology. Stomatology
Palate - microbiology
Pharyngeal Diseases - epidemiology
Pharyngeal Diseases - microbiology
Retrospective Studies
Sex Factors
Tropical mycoses
ulcerated oral lesions
title Oral histoplasmosis associated with HIV infection: a comparative study
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