Effects of Surface Processing of Lactose Carrier Particles on Dry Powder Inhalation Properties of Salbutamol Sulfate

The effects of the surface processing of lactose carrier particles on the dry powder inhalation properties of salbutamol sulfate were investigated. Lactose carrier particles were processed using a high-speed elliptical-rotor-type powder mixer (Theta-Composer®). In the present study, drug/carrier pow...

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Veröffentlicht in:	Chemical & Pharmaceutical Bulletin 2004, Vol.52(8), pp.938-942
Hauptverfasser:	Iida, Kotaro, Inagaki, Yukari, Todo, Hiroaki, Okamoto, Hirokazu, Danjo, Kazumi, Luenberger, Hans
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Inhalation Albuterol - administration & dosage Albuterol - chemistry Bronchodilator Agents - administration & dosage Bronchodilator Agents - chemistry Drug Carriers - administration & dosage Drug Carriers - chemistry dry powder inhalation high-speed elliptical-rotor-type powder mixer Lactose - administration & dosage Lactose - chemistry lactose carrier particle Microscopy, Electron, Scanning Particle Size Powders - chemistry salbutamol sulfate surface processing Surface Properties Temperature X-Ray Diffraction
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