The hypotension evoked by visceral nociception is mediated by delta opioid receptors in the periaqueductal gray

This study tested the hypothesis that the ventrolateral column of the midbrain periaqueductal gray (vlPAG) region mediates the hypotension and bradycardia evoked by visceral nociception. To test this, the local anesthetic lidocaine (2%; 0.5 μl) was microinjected into the vlPAG of halothane-anestheti...

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Veröffentlicht in:	Brain research 2004-09, Vol.1019 (1-2), p.237-245
Hauptverfasser:	Cavun, Sinan, Goktalay, Gokhan, Millington, William R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Central cardiovascular regulation Delta receptor Fundamental and applied biological sciences. Psychology Heart Rate - drug effects Heart Rate - physiology Hypotension - physiopathology Male Motor control and motor pathways. Reflexes. Control centers of vegetative functions. Vestibular system and equilibration Narcotic Antagonists - pharmacology Opioid receptor Pain Pain Measurement - drug effects Pain Measurement - methods Periaqueductal gray Periaqueductal Gray - drug effects Periaqueductal Gray - physiology Rats Rats, Sprague-Dawley Receptors, Opioid, delta - antagonists & inhibitors Receptors, Opioid, delta - physiology Vertebrates: nervous system and sense organs Visceral nociception
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