Hypothesis: one rate-limiting step controls the magnitude of both phases of glucose-stimulated insulin secretion

Department of Molecular Medicine, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853 The biphasic secretory response of pancreatic -cells to abrupt and sustained exposure to glucose is well documented. Some of the ATP-sensitive K + (K ATP ) channel-dependent mechanisms underl...

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Veröffentlicht in:	American Journal of Physiology: Cell Physiology 2004-09, Vol.287 (3), p.C565-C571
Hauptverfasser:	Straub, Susanne G, Sharp, Geoffrey W. G
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cytoplasmic Granules - metabolism Glucose - metabolism Humans Insulin - metabolism Insulin Secretion Islets of Langerhans - metabolism Potassium Channels - metabolism Signal Transduction - physiology
Online-Zugang:	Volltext
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